2299-73-2

Basic information

• Product Name: 4-METHOXYBENZALDEHYDE AZINE
• Synonyms: 4,4'-Dimethoxybenzylideneazine;4-methoxybenzaldazine;4-methoxy-benzaldehyd[(4-methoxyphenyl)methylene]hydrazone;4-Methoxybenzaldehyde [(E)-(4-methoxyphenyl)methylidene]hydrazone;Anisalazine;Benzaldehyde, 4-methoxy-, [(4-methoxyphenyl)methylene]hydrazone;p-Methoxybenzaldazine;p-Methoxybenzaldehyde azine
• CAS NO: 2299-73-2
• Molecular Formula: C₁₆H₁₆N₂O₂
• Molecular Weight: 268.31
• Mol File: 2299-73-2.mol
• Article Data: 58

Chemical Properties

• Melting Point: 167 °C
• Boiling Point: 390.6°Cat760mmHg
• Flash Point: 153.7°C
• Appearance: /
• Density: 1.05g/cm³
• Refractive Index: 1.54
• PKA: 6.74±0.50(Predicted)
• BRN: 1079059
• CAS DataBase Reference: 4-METHOXYBENZALDEHYDE AZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHOXYBENZALDEHYDE AZINE(2299-73-2)
• EPA Substance Registry System: 4-METHOXYBENZALDEHYDE AZINE(2299-73-2)

Safety Data

• Safety Statements: 22-24/25
• TSCA: Yes
• Hazardous Substances Data: 2299-73-2(Hazardous Substances Data)

Usage

General Description

4-METHOXYBENZALDEHYDE AZINE, also known as p-anisaldehyde azine, is an organic compound often used as an intermediate in the production of pharmaceuticals and agrochemicals. It is a white to light yellow crystalline powder with a chemical formula of C14H12N2O2. 4-METHOXYBENZALDEHYDE AZINE is known for its use in the synthesis of various heterocyclic compounds and is commonly used as a key building block in the production of pharmaceuticals due to its versatile reactivity and functional groups. It has potential applications in the field of medicinal chemistry and drug discovery due to its ability to modify the properties of molecules, making it a valuable tool in chemical synthesis.

InChI:InChI=1/C16H16N2O2/c1-19-15-7-3-13(4-8-15)11-17-18-12-14-5-9-16(20-2)10-6-14/h3-12H,1-2H3/b17-11+,18-12u

Upstream product

• 6292-71-3 4-methoxybenzaldehyde semicarbazone 
• 3179-10-0 (E)-1-methoxy-4-(2-nitrovinyl)benzene 
• 123-11-5 4-methoxy-benzaldehyde 
• 874-90-8 4-methoxybenzonitrile 
• 6638-56-8 2,2'-bis[(4-methoxyphenyl)methylene]carbonic dihydrazide 
• 14850-86-3 N'-(4-methoxybenzylidene)benzohydrazide 
• 80414-86-4 3-Hydrazinosulfonyl-5-chlorosalicylic acid 
• 103-13-9 1-(4-methoxyphenyl)-4-methyl-1-penten-3-one 
• 7647-01-0 hydrogenchloride 
• 71-41-0 pentan-1-ol 
• 36640-86-5 phenyl-acetic acid-(4-methoxy-benzylidenehydrazide) 
• 691-38-3 (Z)-4-methyl-2-pentene 
• 110-82-7 cyclohexane 
• 23304-25-8 p-methoxyphenyldiazomethane 

Downstream Products

• 118951-31-8 3,7-bis-(4-methoxy-phenyl)-tetrahydro-pyrazolo[1,2-a]pyrazole-1,2,5,6-tetracarboxylic acid-1,2;5,6-dianhydride 
• 4705-34-4 1,2-bis(4-methoxyphenyl)ethene 
• 4705-34-4 4,4'-dimethoxystilbene 
• 874-90-8 4-methoxybenzonitrile 
• 4334-74-1 4-methoxybenzylidene thiosemicarbazone 
• 622-73-1 4-methoxybenzaldehydephenylhydrazone 
• 28231-25-6 meso-hexestrol dimethyl ether 
• 65655-95-0 3-(4-methoxy-benzylideneamino)-2-(4-methoxy-phenyl)-thiazolidin-4-one 
• 69736-58-9 3-(4-methoxy-benzylideneamino)-2-(4-methoxy-phenyl)-6-trifluoromethyl-2,3-dihydro-[1,3,5]oxadiazin-4-one 
• 36951-42-5 (2-(4-methoxyphenyl)methylene)hydrazolyl-1,3-thiazolidin-4-one 
• 36951-49-2 4-methoxy-benzaldehyde [5-(4-methoxy-benzylidene)-4-oxo-thiazolidin-2-ylidene]-hydrazone 
• 39122-59-3 meso-2,2'-bis-(4-methoxy-phenyl)-6,6'-diphenyl-[3,3']bi[1,3,5]thiadiazinyl-4,4'-dione 
• 17799-70-1 3-(4-methoxy-benzylideneamino)-2-(4-methoxy-phenyl)-2,3-dihydro-benzo[e][1,3]oxazin-4-one 
• 69736-56-7 3-(4-methoxy-benzylideneamino)-2-(4-methoxy-phenyl)-6-trichloromethyl-2,3-dihydro-[1,3,5]oxadiazin-4-one 

Relevant articles and documents

Synthesis and antimicrobial activity of some new coumarin and dicoumarol derivatives

PTC reaction of coumarin derivative 1 with alkyl halides afforded C4 oxygen alkylation products 2a-d in appreciative yield, whereas with phenyl isothiocyanate gives the C3 addition product 4; also, one-pot three-component PTC reactio

Glucose:urea:NH4Cl low melting mixture for the synthesis of symmetric azines

Alternate reaction media have become very important due to the problems created by the highly volatile nature of the solvents. The deep eutectic mixture is a kind of an alternate reaction medium which has emerged in recent years. Low melting mixtures were introduced by making the deep eutectic mixture more cost-effective and renewable by introducing carbohydrates into it. The properties of low melting mixtures include easiness to prepare, usage of low-cost components, biodegradability, solubility in water, easy separation from organic compounds, etc. The low melting mixtures such as glucose:urea:NH4Cl, glucose:ChCl, glucose:urea:ChCl, glycerol:urea:NH4Cl, and ethylene glycol:urea:NH4Cl were used in different ratios for the reactions. The properties such as viscosity, density, acidity, glass transition temperature, and thermal stability were studied. An unusual method for the synthesis of symmetrical azines is introduced wherein benzaldehyde and hydroxylamine are reacted in the presence of glucose:urea:NH4Cl. The method of synthesis needs only less reaction time, temperature and the product was easily separated. The products were confirmed using GC-MS and NMR techniques. The recyclability of glucose:urea:NH4Cl was studied.