2483-48-9 Usage
Description
(+)-(S)-N2,N6-bis[(1,1-dimethylethoxy)carbonyl]-lysine methyl ester is a chemical compound derived from lysine, an essential amino acid. It is commonly used in solid-phase peptide synthesis and as a building block in the production of polypeptides. (+)-(S)-N2,N6-bis[(1,1-dimethylethoxy)carbonyl]-lysine methyl ester features two protected carboxyl groups and a methyl ester group on the lysine side chain, which provides protection for the amino group. This allows for selective deprotection and further modification of the peptide, making it a valuable intermediate in peptide synthesis.
Uses
Used in Biochemistry and Pharmaceutical Research:
(+)-(S)-N2,N6-bis[(1,1-dimethylethoxy)carbonyl]-lysine methyl ester is used as an intermediate in the development and synthesis of various peptides for therapeutic and research purposes. Its role in peptide synthesis is crucial due to its protected carboxyl and amino groups, which enable selective deprotection and further modification of peptides.
Used in Solid-Phase Peptide Synthesis:
In the field of solid-phase peptide synthesis, (+)-(S)-N2,N6-bis[(1,1-dimethylethoxy)carbonyl]-lysine methyl ester is used as a building block for the production of polypeptides. Its protected carboxyl groups facilitate the stepwise assembly of peptide chains, making it an essential component in this synthesis process.
Used in the Production of Polypeptides:
(+)-(S)-N2,N6-bis[(1,1-dimethylethoxy)carbonyl]-lysine methyl ester is also utilized in the production of polypeptides, which are short chains of amino acids. Its protected functional groups allow for the controlled synthesis of these polypeptides, which can be used in various applications, including drug development and research.
Check Digit Verification of cas no
The CAS Registry Mumber 2483-48-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,4,8 and 3 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 2483-48:
(6*2)+(5*4)+(4*8)+(3*3)+(2*4)+(1*8)=89
89 % 10 = 9
So 2483-48-9 is a valid CAS Registry Number.
2483-48-9Relevant articles and documents
PROCESS FOR THE PREPARATION OF LISDEXAMFETAMINE AND RELATED DERIVATIVES
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, (2017/01/19)
The present invention is directed to processes for the preparation of lisdexamfetamine and related derivatives, wherein the processes comprise coupling to racemic or enantiomerically enriched amphetamine and wherein the resulting product is advantageously enantiomerically or diastereomerically enriched in the desired stereoisomer.
HIV PROTEASE INHIBITORS
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Page/Page column 43-44, (2012/05/19)
Compounds of Formula I are disclosed wherein R1, R2, R3A, R3B, R4A, R4B, R5A, R5B, R6A, R6B, R7, R8 and R9 are defined herein. The compounds encompassed by Formula I include compounds which are HIV protease inhibitors and other compounds which can be metabolized in vivo to HIV protease inhibitors. The compounds and their pharmaceutically acceptable salts are useful for the prophylaxis or treatment of infection by HIV and the prophylaxis, treatment, or delay in the onset of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
HIV PROTEASE INHIBITORS
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Page/Page column 97, (2009/05/29)
Compounds of Formula I are disclosed: (I), wherein XA, k, R1, R2, R3, R4, R5, R5A, R6, R6A, R7 and R8 are defined herein. The compounds encompassed by Formula I include compounds which are HIV protease inhibitors and other compounds which can be metabolized in vivo to HIV protease inhibitors. The compounds and their pharmaceutically acceptable salts are useful for the prophylaxis or treatment of infection by HIV and the prophylaxis, treatment, or delay in the onset of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
