2515-61-9

Basic information

• Product Name: 1H-Pyrazole, 4,5-dihydro-1,5-diphenyl-
• CAS NO: 2515-61-9
• Molecular Formula: C15H14N2
• Molecular Weight: 222.29
• Mol File: 2515-61-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazole, 4,5-dihydro-1,5-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole, 4,5-dihydro-1,5-diphenyl-(2515-61-9)
• EPA Substance Registry System: 1H-Pyrazole, 4,5-dihydro-1,5-diphenyl-(2515-61-9)

Safety Data

• Hazardous Substances Data: 2515-61-9(Hazardous Substances Data)

Usage

Type of compound

heterocyclic organic compound

Structure

five-membered ring with two nitrogen atoms

Usage

building block for the synthesis of pharmaceuticals and agrochemicals

Application

intermediate in the production of various organic compounds with biological activity (e.g. anti-cancer drugs, insecticides)

Purpose

used in research and development for the creation of new drugs and chemical products.

Upstream product

• 1216-15-5 cinnamaldehyde phenylhydrazone 
• 13599-22-9 1,5-diphenylpyrazole-3-carboxylic acid 
• 13370-06-4 1,5-diphenyl-4-pyrazolin-3-one 
• 622-11-7 α-nitroformaldehyde phenylhydrazone 

Downstream Products

• 742-01-8 1,3,5-triphenyl-4,5-dihydro-1H-pyrazole 
• 17355-48-5 1,5-diphenyl-3-phenylazo-4,5-dihydro-1H-pyrazole 
• 19762-42-6 3-formyl-1,5-diphenyl-2-pyrazoline 

Relevant articles and documents

1,3-Dipolar Cycloadditions, 87. Contributions to the Chemistry of N-Phenylnitrilimine

The N-phenyl derivative 7 is introduced as the first monosubstituted and interceptible nitrilimine whereas the cycloadditions of disubstituted representatives have been preparatively utilized in the past.Photolysis of 2-phenyltetrazole in the presence of methyl acrylate gives rise to methyl 1-phenyl-2-pyrazoline-5-carboxylate which on further irradiation suffers ring cleavage.The sodium salt of α-nitroformaldehyde phenylhydrazone (15) eliminates NaNO2 in refluxing acetonitrile whereby the intermediate 7 is accepted in situ by acrylic ester, styrene and norbornene.The interaction of methyl acrylate with the anionic precursor 15 furnishes further products.The formal dimer of 7, the 1,4-diphenyl-1,4-dihydro-1,2,4,5-tetrazine, is probably formed by reaction of 7 with 15.