260046-15-9

Basic information

• Product Name: (2-chloro-5-methyl-phenyl)-(2-chloro-pyrimidin-4-yl)-amine
• CAS NO: 260046-15-9
• Molecular Weight: 254.119
• Mol File: 260046-15-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2-chloro-5-methyl-phenyl)-(2-chloro-pyrimidin-4-yl)-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (2-chloro-5-methyl-phenyl)-(2-chloro-pyrimidin-4-yl)-amine(260046-15-9)
• EPA Substance Registry System: (2-chloro-5-methyl-phenyl)-(2-chloro-pyrimidin-4-yl)-amine(260046-15-9)

Safety Data

• Hazardous Substances Data: 260046-15-9(Hazardous Substances Data)

Upstream product

• 3934-20-1 2,6-Dichloropyrimidine 
• 95-81-8 2-chloro-5-methylaniline 

Relevant articles and documents

Cyclin-dependent kinase 4 inhibitors as a treatment for cancer. Part 2: Identification and optimisation of substituted 2,4-bis anilino pyrimidines

Through chemical modification and X-ray crystallography we identified the 2,4-bis anilino pyrimidines as potent inhibitors of CDK4. Herein, we describe the optimisation of this series.