260243-56-9

Basic information

• Product Name: 5-amino-4-oxo-2-m-tolylimino-thiazolidine-5-carboxylic acid ethyl ester
• CAS NO: 260243-56-9
• Molecular Weight: 293.346
• Mol File: 260243-56-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-amino-4-oxo-2-m-tolylimino-thiazolidine-5-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-amino-4-oxo-2-m-tolylimino-thiazolidine-5-carboxylic acid ethyl ester(260243-56-9)
• EPA Substance Registry System: 5-amino-4-oxo-2-m-tolylimino-thiazolidine-5-carboxylic acid ethyl ester(260243-56-9)

Safety Data

• Hazardous Substances Data: 260243-56-9(Hazardous Substances Data)

Upstream product

• 621-40-9 (3-methylphenyl)thiourea 
• 81918-04-9 diethyl α-acetamido-α-bromomalonate 

Downstream Products

• 260243-69-4 8-(4-methoxy-phenyl)-7-thioxo-2-m-tolylimino-1-thia-3,6,8-triaza-spiro[4.4]nonane-4,9-dione 
• 260243-68-3 7-thioxo-8-p-tolyl-2-m-tolylimino-1-thia-3,6,8-triaza-spiro[4.4]nonane-4,9-dione 

Relevant articles and documents

On the synthesis of novel spiroglucosides and fused ring heterocycles from diethyl α-acetamido-α-bromomalonate

Diethyl α-acetamido-α-bromomalonate 1 with thiocarbamides 2 and 4- substituted thiosemicarbazides 8 give 2-alkyl/arylimino-5-amino-5-carbethoxy- 4-oxo-(3H)-thiazoles 3 and 2-alkyl/arylimino-6-amino-6-carbethoxy-5-oxo-(3H, 4H)-1,3,4-thiadiazines 9 respectively. Compounds 3 and 9 with arylisothiocyanate 4 afford spiro [4.4]nonane and spiro[5.4]decane derivatives. These spiroheterocycles on reaction with 2,3,4,6-tetrabenzoyl- α-D-glucopyranosyl bromide 6 give novel spiroglucosides. Also compounds 3 and 9 with hydrazine hydrate give fused pyrazolo[5,4-d]thiazole and pyrazolo[5,4-e]thiadiazine derivatives respectively. The characterisation of the products has been done on the basis of spectral (IR, 1H NMR, and 13C NMR) data.