28165-60-8

Basic information

• Product Name: 2,3-DICHLORO-6-NITROPHENOL
• Synonyms: 2,3-DICHLORO-6-NITROPHENOL
• CAS NO: 28165-60-8
• Molecular Formula: C₆H₃Cl₂NO₃
• Molecular Weight: 208
• Product Categories: Aromatic Phenols
• Mol File: 28165-60-8.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2,3-DICHLORO-6-NITROPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DICHLORO-6-NITROPHENOL(28165-60-8)
• EPA Substance Registry System: 2,3-DICHLORO-6-NITROPHENOL(28165-60-8)

Safety Data

• Hazardous Substances Data: 28165-60-8(Hazardous Substances Data)

Usage

Compound type

Nitrophenol

Physical form

Yellow crystalline substance

Melting point

132-133 °C

Uses

Pesticide, fungicide, wood preservative

Antimicrobial properties

Bactericide, algicide, fungicide in water and industrial applications

Toxicity

Toxic and harmful to aquatic organisms

Hazard classification

Hazardous substance, must be handled with caution.

Upstream product

• 576-24-9 2,3-dichlorophenol 
• 99-54-7 3,4-dichloronitrobenzene 
• 207238-21-9 Carbonic acid 2,3-dichloro-phenyl ester ethyl ester 

Downstream Products

• 63105-60-2 2,3-dichloro-6-nitrobenzoic acid methyl ester 
• 116278-69-4 5,6-dichloro-2-aminophenol 

Relevant articles and documents

Fragment-Based Discovery of Novel Potent Sepiapterin Reductase Inhibitors

Genome-wide-association studies in chronic low back pain patients identified sepiapterin reductase as a high interest target for developing new analgesics. Here we used 19F NMR fragment screening for the discovery of novel, ligand-efficient SPR

IL-8 RECEPTOR ANTAGONISTS

Novel IL-8 receptor antagonists and methods of using them are provided.

Practical application of the palladium-catalyzed amination in phenylpiperazine synthesis: An efficient synthesis of a metabolite of the antipsychotic agent aripiprazole

A metabolite of Aripiprazole (1), 7-[4-[4-(2,3-dichloro-4- hydroxyphenyl)-1-piperaziyl]butoxy]-3,4-dihydro-2(1H)-quinolinone (2), was prepared by the coupling reaction of 1-(4-benzyloxy-2,3-dichlorophenyl) piperazine (11) with 7-(4-chlorobutoxy)-3,4-dihydro-2(1H)-quinolinone (16). The palladium-catalyzed amination of contiguous tri- and tetra-substituted benzenes with piperazine derivatives was investigated. The key intermediate 11 was efficiently prepared using the palladium-catalyzed amination of phenyl bromide 15 with piperazine.