2905-54-6

Basic information

• Product Name: METHYL 2,3-DICHLOROBENZOATE
• Synonyms: METHYL 2,3-DICHLOROBENZOATE;2,3-DICHLOROBENZOIC ACID METHYL ESTER;RARECHEM AL BF 0205;2,3-Dichlorobenzoic methylester;Methyl 2,3-dichlorobenzoate,97%;Methyl 2,3-dichlorobenzoate,98+%;Benzoic acid, 2,3-dichloro-, Methyl ester;2,3-dichloro-benzoicacimethylester
• CAS NO: 2905-54-6
• Molecular Formula: C₈H₆Cl₂O₂
• Molecular Weight: 205.04
• Product Categories: Aromatic Esters
• Mol File: 2905-54-6.mol
• Article Data: 10

Chemical Properties

• Melting Point: 33-38 °C
• Boiling Point: 294.45°C (rough estimate)
• Flash Point: 110 °C
• Appearance: /
• Density: 1.36
• Vapor Pressure: 0.00703mmHg at 25°C
• Refractive Index: 1.5537
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: METHYL 2,3-DICHLOROBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2,3-DICHLOROBENZOATE(2905-54-6)
• EPA Substance Registry System: METHYL 2,3-DICHLOROBENZOATE(2905-54-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26
• Hazardous Substances Data: 2905-54-6(Hazardous Substances Data)

Usage

Chemical Properties

white crystals

InChI:InChI=1/C8H6Cl2O2/c1-12-8(11)5-3-2-4-6(9)7(5)10/h2-4H,1H3

Upstream product

• 114125-02-9 1,6,7,7-Tetrachlor-cis-bicyclo<4.1.0>hept-3-en-2-ol 
• 50-45-3 2,3-dichlorbenzoic acid 
• 17287-03-5 trimethylsulphonium hydroxide 
• 31273-66-2 ethyl 2,3-dichlorobenzoate 
• 114125-01-8 1,6,7,7-Tetrachlor-2-trimethylsilyloxy-cis-bicyclo<4.1.0>hept-3-en 
• 67-56-1 methanol 
• 95-50-1 1,2-dichloro-benzene 
• 74-88-4 methyl iodide 

Downstream Products

• 191091-39-1 1-(2,3-dichlorophenyl)-1-hydroxy-2-(2-pyridyl)ethylene 
• 662142-37-2 1-(2,3-dichlorophenyl)-1-hydroxy-2-methyl-2-(2-pyridyl)ethylene 
• 75473-09-5 2,3-dichlorobenzoylacetonitrile 
• 3218-45-9 2,3-dichlorophenylacetonitrile 
• 10236-60-9 (2,3-dichlorophenyl)acetic acid 
• 550377-03-2 [cyclohexyl-(2-{4-[5-(2,3-dichloro-phenyl)-2-methyl-2H-pyrazol-3-yl]-piperidin-1-yl}-2-oxo-ethylcarbamoyl)-methyl]-carbamic acid tert-butyl ester 
• 716370-78-4 4-[5-(2,3-dichlorophenyl)-4-methyl-2H-pyrazol-3-yl]piperidine-1-carboxylic acid tert-butyl ester 
• 716371-44-7 4-[5-(2,3-dichlorophenyl)-2-methyl-2H-pyrazol-3-yl]piperidine-1-carboxylic acid tert-butyl ester 
• 550377-00-9 4-[5-(2,3-dichlorophenyl)-1-methyl-1H-pyrazol-3-yl]piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

New Syntheses of Chloro-Substituted Derivatives of Tropone

The Diels-Alder reaction of donor-substituted 1,3-dienes with tetrachlorocyclopropene leads to novel bicycloheptenes, which on acidic hydrolysis and oxidation yield a new series of chloro-substituted derivatives of tropone by way of elimination of hydrogen chloride concerted with an electrocyclic opening of the three membered ring.

COMPOUNDS, COMPOSITIONS AND METHODS OF USE

Herein, compounds, compositions and methods for modulating inclusion formation and stress granules in cells related to the onset of neurodegenerative diseases, musculoskeletal diseases, cancer, ophthalmological diseases, and viral infections are described.

PYRAZOLOPYRIMIDINE DERIVATIVES AS PI3 KINASE INHIBITORS

The present invention relates to compounds of formula (I) in which R1, R2, R3 and n have the meaning given in the specification and also relates to the use of these pyrazolopyrimidine derivatives for the modulation, notably the inhibition of the activity or function of the phosphoinositide 3'OΗ kinase family (hereinafter PI3 kinases), wherein the compounds of formula (I) are described as selective inhibitors of PI3K[beta] activity.