29664-59-3

Basic information

• Product Name: 2-methylpropyl hydroxy(phenyl)acetate
• Synonyms: Benzeneacetic acid, .alpha.-hydroxy-, 2-methylpropyl ester
• CAS NO: 29664-59-3
• Molecular Formula: C₁₂H₁₆O₃
• Molecular Weight: 208.2536
• Mol File: 29664-59-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 307.8°C at 760 mmHg
• Flash Point: 124.7°C
• Density: 1.093g/cm³
• Vapor Pressure: 0.000308mmHg at 25°C
• Refractive Index: 1.517
• CAS DataBase Reference: 2-methylpropyl hydroxy(phenyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methylpropyl hydroxy(phenyl)acetate(29664-59-3)
• EPA Substance Registry System: 2-methylpropyl hydroxy(phenyl)acetate(29664-59-3)

Safety Data

• Hazardous Substances Data: 29664-59-3(Hazardous Substances Data)

Upstream product

• 611-73-4 Benzoylformic acid 
• 1334313-49-3 (Z)-isobutyl 2-phenyl-2-(2-tosylhydrazono)acetate 
• 31197-67-8 iso-butyl 2-oxo-2-phenylacetate 
• 78-83-1 2-methyl-propan-1-ol 
• 611-71-2 MANDELIC ACID 

Downstream Products

• 31197-67-8 iso-butyl 2-oxo-2-phenylacetate 
• 136205-58-8 (S)-α-hydroxyphenylacetic acid iso-butyl ester 
• 136205-59-9 (R)-α-hydroxyphenylacetic acid iso-butyl ester 

Relevant articles and documents

Zirconocene-catalyzed direct (trans)esterification of acyl acids (esters) and alcohols in a strict 1:1 ratio under solvent-free conditions

A highly efficient way for the direct (trans)esterification of acyl acids (esters) and alcohols in a strict 1:1 ratio using a zirconocene complex (1, 1 mol%), a strong Lewis acid of good water tolerance, as a catalyst under solvent-free conditions has been developed. A wide range of acid and alcohol (esters) substrates undergo (trans)esterification to produce carboxylic ester motifs in moderate to good or excellent yields with good functional tolerance, such as that towards C-Br as well as CC and CC bonds. And complex 1 can be recycled six times without showing a significant decline in catalytic efficiency. It was demonstrated that cyclandelate, which is used to treat high blood pressure as well as heart and blood-vessel diseases, can be directly synthesized on a gram scale with 81% yield (6.70 g) using complex 1.

1,3-Bis(2,4,6-trimethylphenyl)imidazolium chloride in combination with triethylamine: An improved catalytic system for hydroacylation/reduction of activated ketones

A rapid, economic, and high yielding methodology has been developed for hydroacylation/reduction of activated ketones by using 1,3-bis(2,4,6- trimethylphenyl)imidazolium chloride as a catalyst in combination with triethylamine. The reaction proceeded at an ambient temperature via generating N-heterocyclic carbene in situ that interacted with the (hetero)aryl aldehyde employed. While the reduction of ketones takes place in MeOH, the hydroacylation process was found to be effective in THF for both electron rich and deficient aldehydes.

N-alkyl-4-boronopyridinium halides versus boric acid as catalysts for the esterification of α-hydroxycarboxylic acids

(Chemical Equation Presented) Boric acid is a highly effective catalyst for the dehydrative esterification reaction between equimolar mixtures of α-hydroxycarboxylic acids and alcohols. In contrast, N-methyl-4- boronopyridinium iodide (2a) is a more effective catalyst than boric acid for the similar esterification in excess alcohol. A heterogeneous catalyst, such as N-polystyrene-bound 4-boronopyridinium chloride, is also an effective catalyst and can be recovered by filtration.