31197-66-7

Basic information

• Product Name: ISOPROPYLPHENYLGLYOXYLATE
• Synonyms: OXOPHENYL ACETIC ACID ISOPROPYL ESTER;ISOPROPYLPHENYLGLYOXYLATE
• CAS NO: 31197-66-7
• Molecular Formula: C₁₁H₁₂O₃
• Molecular Weight: 192.21
• Mol File: 31197-66-7.mol
• Article Data: 46

Chemical Properties

• Boiling Point: 153.5-154.4 °C(Press: 12 Torr)
• Appearance: /
• Density: 1.102±0.06 g/cm3(Predicted)
• CAS DataBase Reference: ISOPROPYLPHENYLGLYOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ISOPROPYLPHENYLGLYOXYLATE(31197-66-7)
• EPA Substance Registry System: ISOPROPYLPHENYLGLYOXYLATE(31197-66-7)

Safety Data

• Hazardous Substances Data: 31197-66-7(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 52, p. 5733, 1987 DOI: 10.1021/jo00235a017

Upstream product

• 611-73-4 Benzoylformic acid 
• 67-63-0 isopropyl alcohol 
• 6831-82-9 potassium isopropoxide 
• 91851-05-7 2-<(4-chlorophenyl)amino>-2-methoxy-1-phenylethanone 
• 25726-04-9 phenylglyoxylyl chloride 
• 591-50-4 iodobenzene 
• 201230-82-2 carbon monoxide 
• 1074-12-0 phenylglyoxal hydrate 
• 2902-69-4 2,2,2-trichloroacetophenone 
• 7402-45-1 α,α,α-tribromoacetophenone 
• 683-60-3 sodium isopropylate 
• 50417-71-5 (benzoyl)PdI(triphenylphosphine)2 
• 932-87-6 1-Bromo-2-phenylacetylene 
• 140-92-1 potassium isopropylxanthate 

Downstream Products

• 53439-96-6 (S)-α-hydroxyphenylacetic acid iso-propyl ester 
• 959153-12-9 isopropyl 2-hydroxy-2-phenylpent-4-enoate 
• 1345971-21-2 2-propanyl 2-hydroxyl-2-(4-methoxyphenyl)-phenylacetate 
• 1361345-91-6 C₁₈H₂₀O₃ 
• 29916-14-1 (S)-ethyl 2-hydroxy-2-phenylpropanoate 
• 2406-23-7 (R)-ethyl 2-hydroxy-2-phenylpropanoate 
• 887617-78-9 isopropyl 2-hydroxy-2-phenylpropanoate 

Relevant articles and documents

Copper on charcoal: Cu0nanoparticle catalysed aerobic oxidation of α-diazo esters

By using a charcoal supported nano Cu0catalyst (Cu/C), a highly efficient oxidation of α-diazo esters to α-ketoesters with molecular oxygen as the sole oxidant has been developed. In the presence of the Cu/C catalyst, 2-aryl-α-diazo esters with both electron-donating and electron-withdrawing groups can be oxidized to the corresponding α-ketoesters efficiently. Furthermore, this Cu/C catalyst can catalyse the reaction of aryl α-diazo ester with water to form aryl ketoester, 2-aryl-2-hydroxyl acetate ester and 2-aryl acetate ester. In this case, water is split by α-diazo ester, and the diazo group is displaced by the oxygen or hydrogen atom in water. Mechanistic investigation showed that the reaction of α-diazo ester with oxygen proceeds through a radical pathway. In the presence of 2,2,6,6-tetramethyl piperidine nitrogen oxide, the reaction of α-diazo ester with oxygen is dramatically inhibited. Furthermore, the reaction of α-diazo ester with water is investigated by an isotopic tracer method, and GCMS detection showed that a disproportionation reaction occurred between α-diazo ester and water.

[Fe(bpy)3]2+-based porous organic polymers with boosted photocatalytic activity for recyclable organic transformations

Three rigid metal porous organic polymers (POPs) based on an iron(ii) complex are prepared from the condensation reactions of an octahedral [Fe(bpy)3]2+-cored hexaaldehyde and three rod-like aromatic diamines. The POPs have been studied as the first series of earth-abundant metal complex-connected photocatalysts for heterogeneous visible light-driven oxidation of benzyl halides and enantioselective α-alkylation of aldehydes. Both yields and enantioselectivities of the reactions catalyzed by one of the POPs, which possesses the largest porosity, rival or even surpass those of the reactions homogeneously catalyzed by control [Fe(bpy)3]2+complexes. Moreover, POP catalysts are highly stable and exhibit a considerable activity after recycling 10 times.

Controllable chemoselectivity in the coupling of bromoalkynes with alcohols under visible-light irradiation without additives: Synthesis of propargyl alcohols and α-ketoesters

The chemoselectivity of visible-light-induced coupling reactions of bromoalkynes with alcohols can be controlled by simple changes to the reaction atmosphere (N2 or O2). A N2 atmosphere favours propargyl alcohols via a direct C-C coupling process, whereas an O2 atmosphere results in the generation of α-ketoesters through the oxidative CC/C-O coupling pathway.