32123-84-5

Basic information

• Product Name: Methyl(α-methylenebenzyl) ketone
• Synonyms: 3-Phenyl-3-buten-2-one;Methyl(α-methylenebenzyl) ketone;Nsc291306
• CAS NO: 32123-84-5
• Molecular Formula: C₁₀H₁₀O
• Molecular Weight: 146.188
• Mol File: 32123-84-5.mol
• Article Data: 27

Chemical Properties

• Boiling Point: 271.4 °C at 760 mmHg
• Flash Point: 97.1 °C
• Appearance: /
• Density: 0.981 g/cm³
• Vapor Pressure: 0.00646mmHg at 25°C
• Refractive Index: 1.518
• CAS DataBase Reference: Methyl(α-methylenebenzyl) ketone(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl(α-methylenebenzyl) ketone(32123-84-5)
• EPA Substance Registry System: Methyl(α-methylenebenzyl) ketone(32123-84-5)

Safety Data

• Hazardous Substances Data: 32123-84-5(Hazardous Substances Data)

Usage

Description

Methyl(α-methylenebenzyl) ketone, also known as 3-Phenyl-3-buten-2-one, is an organic compound characterized by its distinct aromatic structure and functional groups. It is a derivative of ketones with a unique molecular arrangement that contributes to its specific properties and applications.

Uses

Used in the Fragrance Industry:
Methyl(α-methylenebenzyl) ketone is used as an odorant for masking, scenting, and odorization of various products, particularly in the fragrance industry. Its aromatic properties make it suitable for enhancing the smell of different items, providing a pleasant and lasting scent.
Used in the Petroleum Industry:
Methyl(α-methylenebenzyl) ketone is also utilized in the petroleum industry as an additive for hydrocarbon oils, fuels, and petroleum products. It serves to improve the odor profile of these products, making them more acceptable to consumers and ensuring a better overall experience during use.

InChI:InChI=1/C10H10O/c1-8(9(2)11)10-6-4-3-5-7-10/h3-7H,1H2,2H3

Upstream product

• 51-80-9 bis-(dimethylamino)methane 
• 103-79-7 1-phenyl-acetone 
• 30354-18-8 N,N-dimethyl(methylene)ammonium chloride 
• 111-34-2 -butyl vinyl ether 
• 1431-79-4 4,4-dimethyl-2-bromocyclohex-2-en-1-one 
• 31357-84-3 (E)-α-Phenyl-β-chlorcrotonaldehyd 
• 31357-83-2 (Z)-α-Phenyl-β-chlorcrotonaldehyd 
• 119044-12-1 (E)-2-phenyl-3-phenylthio-but-2-enal 
• 119044-21-2 (Z)-2-phenyl-3-phenylthio-but-2-enal 
• 62-53-3 aniline 
• 59417-88-8 (E/Z)-4-phenyl-2-((trimethylsilyl)oxy)-2-butene 
• 6051-52-1 2-phenylbut-3-en-2-ol 
• 103-82-2 phenylacetic acid 
• 178425-56-4 1,1,2-tribromo-2-phenylcyclopropane 

Downstream Products

• 1460349-41-0 N-((2S)-3-phenylbut-3-en-2-yl)acetamide 
• 1460349-40-9 N-((2R)-3-phenylbut-3-en-2-yl)acetamide 
• 1007-71-2 1-(1-phenyl-cyclopropyl)-ethanone 
• 4360-47-8 cinnamonitrile 
• 6249-81-6 3-phenyl-but-3-en-2-ol 

Relevant articles and documents

Asymmetric Catalytic Epoxidation of Terminal Enones for the Synthesis of Triazole Antifungal Agents

An enantioselective epoxidation of α-substituted vinyl ketones was realized to construct the key epoxide intermediates for the synthesis of various triazole antifungal agents. The reaction proceeded efficiently in high yields with good enantioselectivities by employing a chiral N,N′-dioxide/ScIII complex as the chiral catalyst and 35% aq. H2O2 as the oxidant. It enabled the facile transformation for optically active isavuconazole, efinaconazole, and other potential antifungal agents.

METHOD FOR PREPARING CHLORINATED KETONE COMPOUNDS

PROBLEM TO BE SOLVED: To provide a method for efficiently producing a α-methylene ketone compound, which is widely found in natural products and is known as a biologically active substance, by a method in which an α, α-disubstituted allyl alcohol compound is used as a raw material, and an expensive oxidizing agent such as a heavy metal system is not used and an environmental load is reduced. SOLUTION: An α, α-disubstituted allyl alcohol compound represented by general formula (1) (wherein R1 and R2 each represents an alkyl group, an aromatic hydrocarbon group, or an alicyclic hydrocarbon group; alternatively, R1 and R2 may form together an aliphatic hydrocarbon ring), is oxidized in the presence of tetraalkylammonium hypochlorite to give a chlorinated ketone compound. This chlorinated ketone compound can be made into an α-methylene ketone compound by dehydrochlorination in the presence of a base. SELECTED DRAWING: None COPYRIGHT: (C)2021,JPOandINPIT

Enantioselective Bromolactonization of Trisubstituted Olefinic Acids Catalyzed by Chiral Pyridyl Phosphoramides

Enantioselective bromolactonization of trisubstituted olefinic acids producing synthetically useful chiral lactones with two contiguous asymmetric centers has remained mainly unexplored except for the 6-exo cyclization mode. In this work, the 5-exo- and 6