51-80-9 Usage
Description
N,N,N',N'-Tetramethyldiaminomethane, also known as TMM, is an organic compound with the chemical formula (CH3)2NCH2N(CH3)2. It is a slightly yellow liquid and is commonly used as a reagent in various chemical reactions.
Uses
Used in Pharmaceutical Industry:
N,N,N',N'-Tetramethyldiaminomethane is used as a reagent for the synthesis of the Mannich intermediate, which is an important compound in the pharmaceutical industry. The Mannich intermediate is a key component in the production of various drugs, including antibiotics, antifungals, and anti-inflammatory medications.
Used in Chemical Synthesis:
In the field of chemical synthesis, N,N,N',N'-Tetramethyldiaminomethane is used as a reagent to facilitate the formation of the Mannich intermediate. This intermediate is crucial for the synthesis of various organic compounds, which can be used in a wide range of applications, such as the production of dyes, polymers, and other specialty chemicals.
Used in Research and Development:
N,N,N',N'-Tetramethyldiaminomethane is also utilized in research and development laboratories for the synthesis of novel compounds and the study of various chemical reactions. Its versatility as a reagent makes it a valuable tool for chemists working on the development of new materials and pharmaceuticals.
Safety Profile
Poison by intraperitoneal route. Flammable liquid and very dangerous fire hazard when exposed to powerful oxidizers, heat or open flame. When heated to decomposition it emits toxic fumes of NOx. See also AMINES.
Check Digit Verification of cas no
The CAS Registry Mumber 51-80-9 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 5 and 1 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 51-80:
(4*5)+(3*1)+(2*8)+(1*0)=39
39 % 10 = 9
So 51-80-9 is a valid CAS Registry Number.
51-80-9Relevant articles and documents
Weingarten,Miles
, p. 668,669 (1968)
Hancock,Dickinson
, p. 783 (1973)
Siloxymethylamines as Aminomethylation Reagents for Amines Leading to Labile Diaminomethanes That can be Trapped as Their [Mo(CO)4] Complexes
Sharma, Hemant K.,Gonzalez, Paulina E.,Craig, Alexander L.,Chakrabarty, Sanchita,Metta-Maga?a, Alejandro,Pannell, Keith H.
, p. 7363 - 7366 (2016/05/24)
Compound Et3SiOCH2NMe2 transfers Me2NCH2 to R2NH (R2=Et2, PhMe, [Cr(η6-C6H5)(CO)3]Me, PhH) to form previously unknown diaminomethanes, Me2NCH2NR2 and, in the case of R2=PhH, the triamine Me2NCH2N(Ph)CH2NMe2. The diaminomethanes exhibit an unreported disproportionation to a mixture of (R2N)2CH2, (Me2N)2CH2, and Me2NCH2NR2, which can be trapped as their [Mo(CO)4(diamine)] complexes. Whereas PhMeNCH2NMe2 is a labile material, the metal-substituted ([(η6-C6H5)Cr(CO)3]MeNCH2NMe2 is a stable material. The triamine Me2NCH2N(Ph)CH2NMe2 is unstable with respect to transformation to 1,3,5-triphenyltriazine, but is readily trapped as the bidentate-triamineMo(CO)4. All metal complexes were characterized by single-crystal X-ray diffraction.
Reactions of zirconium amide amidinates with dioxygen. Observation of an unusual peroxo intermediate in the formation of oxo compounds
Lamb, Adam C.,Lu, Zheng,Xue, Zi-Ling
supporting information, p. 10517 - 10520 (2014/12/10)
Reaction of d0 Zr(NMe2)2[MeC(N iPr)2]2 (1) with O2 at -30°C gives three Zr containing products: a peroxo trimer {(μ-η2: η2-O2)Zr[MeC(NiPr)2] 2}3 (2), an oxo dimer {(μ-O)Zr[MeC(N iPr)2]2}2 (3), and an oxo polymer {(μ-O)Zr[MeC(NiPr)2]2}n (4). 2 is a rarely observed peroxo complex from the reaction of a d0 complex with O2. This journal is the Partner Organisations 2014.