35761-27-4 Usage
Description
METHYL 2-(S)-[N-CARBOBENZYLOXY]AMINO-3-AMINOPROPIONATE, HYDROCHLORIDE is a chemical compound that serves as an important building block for the synthesis of peptides containing diaminopimelic acid (DAP) residues. It is a key component in the production of various bioactive peptides, such as bleomycins, edeines, and tuberactinomycins, which have significant applications in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
METHYL 2-(S)-[N-CARBOBENZYLOXY]AMINO-3-AMINOPROPIONATE, HYDROCHLORIDE is used as a key building block for the synthesis of bioactive peptides containing DAP residues. Its role in the production of peptides such as bleomycins, edeines, and tuberactinomycins makes it a valuable component in the development of pharmaceuticals with potential therapeutic applications.
Used in Peptide Synthesis:
METHYL 2-(S)-[N-CARBOBENZYLOXY]AMINO-3-AMINOPROPIONATE, HYDROCHLORIDE is used as a crucial intermediate in the synthesis of peptides with DAP residues. Its presence in the synthesis process allows for the creation of complex peptide structures that can be further utilized in various applications, including drug development and research.
Used in Research and Development:
METHYL 2-(S)-[N-CARBOBENZYLOXY]AMINO-3-AMINOPROPIONATE, HYDROCHLORIDE is used as a research tool for studying the properties and potential applications of peptides containing DAP residues. Its role in the synthesis of bioactive peptides makes it an essential component in the ongoing research and development efforts aimed at discovering new therapeutic agents and understanding their mechanisms of action.
Check Digit Verification of cas no
The CAS Registry Mumber 35761-27-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,7,6 and 1 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 35761-27:
(7*3)+(6*5)+(5*7)+(4*6)+(3*1)+(2*2)+(1*7)=124
124 % 10 = 4
So 35761-27-4 is a valid CAS Registry Number.
InChI:InChI=1/C12H16N2O4/c1-17-11(15)10(7-13)14-12(16)18-8-9-5-3-2-4-6-9/h2-6,10H,7-8,13H2,1H3,(H,14,16)/t10-/m0/s1
35761-27-4Relevant articles and documents
Total Synthesis and Biological Evaluation of Paenilamicins from the Honey Bee Pathogen Paenibacillus larvae
Bulatov, Timur,Dang, Tam,Ebeling, Julia,Genersch, Elke,Gensel, Sebastian,Koller, Timm O.,Mainz, Andi,Süssmuth, Roderich D.,Voigt, Kerstin,Wilson, Daniel N.
, p. 288 - 296 (2022/01/19)
Paenilamicins are a group of complex polycationic peptide secondary metabolites with antibacterial and antifungal activities produced by the devastating honey bee brood pathogen Paenibacillus larvae causing the lethal brood disease American Foulbrood (AFB
COMPOSITIONS AND METHODS FOR THE TREATMENT OF FUNGAL INFECTIONS
-
Page/Page column 94, (2015/03/28)
Compositions and methods for the treatment of fungal infections including compounds containing a pathogen pattern recognition receptor ligand and a β 1,3-glucan synthase inhibitor are disclosed. In particular, compounds containing a lipopeptide moiety and
Sulfate Encapsulation in Supramolecular Structures from L -Asparagine-Derived 2,5-Diketopiperazine Scaffolds: Anion Binding
Naini, Santhosh Reddy,Lalancette, Roger A.,Gorlova, Olga,Ramakrishna, Kallaganti V. S.,Yadav, Jhillu Singh,Ranganathan, Subramania
, p. 7015 - 7022 (2016/02/19)
We report a new sulfate receptor, anchored onto 2,5-diketopiperazine units, which results in the formation of two types of supramolecules; one in which the sulfate ion guest fits snugly into extended cavities and the other in which the guest is sandwiched between layers. In each case, the anion is held by six hydrogen bonds from the host. 1H NMR spectroscopic solution studies enabled the construction of Job plots, and calculation of stoichiometry and association constants. These findings are of possible significance in drug design and for construction of combinatorial libraries.
