3968-48-7

Basic information

• Product Name: Methanone, phenyl(1-phenyl-1H-pyrazol-4-yl)-
• CAS NO: 3968-48-7
• Molecular Formula: C16H12N2O
• Molecular Weight: 248.284
• Mol File: 3968-48-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Methanone, phenyl(1-phenyl-1H-pyrazol-4-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, phenyl(1-phenyl-1H-pyrazol-4-yl)-(3968-48-7)
• EPA Substance Registry System: Methanone, phenyl(1-phenyl-1H-pyrazol-4-yl)-(3968-48-7)

Safety Data

• Hazardous Substances Data: 3968-48-7(Hazardous Substances Data)

Upstream product

• 1126-00-7 1-phenylpyrazole 
• 98-88-4 benzoyl chloride 
• 141998-88-1 4-tributylstannyl-1-phenylpyrazole 
• 101350-45-2 phenyl-(1-phenyl-1H-pyrazol-4-yl)-methanol 
• 7647-01-0 hydrogenchloride 
• 50-00-0 formaldehyd 
• 1131-80-2 (E)-3-(N,N-dimethylamino)-1-phenyl-2-propen-1-one 
• 59-88-1 phenylhydrazine hydrochloride 
• 67-68-5 dimethyl sulfoxide 
• 15115-52-3 4-bromo-1-phenyl-1H-pyrazole 
• 5908-41-8 benzoyltrimethylsilane 
• 100-63-0 phenylhydrazine 
• 54605-72-0 1-phenyl-1H-pyrazole-4-carbaldehyde 
• 90920-94-8 benzoyl-malonaldehyde 

Downstream Products

• 23972-16-9 phenyl-(1-phenyl-1H-pyrazol-4-yl)-methanone oxime 
• 23972-17-0 phenyl-(1-phenyl-1H-pyrazol-4-yl)-methanone oxime 

Relevant articles and documents

DMSO as a C1 Source for [2 + 2 + 1] Pyrazole Ring Construction via Metal-Free Annulation with Enaminones and Hydrazines

A cascade reaction between enaminones, hydrazines, and dimethyl sulfoxide (DMSO) for the synthesis of 1,4-disubstituted pyrazoles catalyzed by molecular iodine in the presence of Selectfluor has been realized. DMSO plays a dual role as the C1 source and the reaction medium. In addition, the synthesis of 1,3,4-trisubstituted pyrazoles using aldehydes as alternative C1 building blocks has also been achieved.

Synthesis of new benzylic ethers of oximes derived from 1-phenyl- pyrazole compounds

In the scope of a research program aiming at the synthesis and pharmacological evaluation of new antithrombotic agents via rational molecular design, we describe in this paper the synthesis of benzyl ethers of aryl-pyrazolic oxime derivatives. Ethers' (2a-2c) and (3a-3c) are derived from 4-formyl-1-N-phenylpyrazole (4) in good yield. Designed as interphenylenic analogues of the ridogrel (1), one expects these compounds to present dual properties, i.e., thromboxane A2 receptors antagonism and thromboxane synthetase inhibition.