4094-37-5

Basic information

• Product Name: Benzene, 1-methyl-4-[(4-nitrophenyl)sulfonyl]-
• CAS NO: 4094-37-5
• Molecular Formula: C13H11NO4S
• Molecular Weight: 277.301
• Mol File: 4094-37-5.mol
• Article Data: 22

Chemical Properties

• CAS DataBase Reference: Benzene, 1-methyl-4-[(4-nitrophenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-methyl-4-[(4-nitrophenyl)sulfonyl]-(4094-37-5)
• EPA Substance Registry System: Benzene, 1-methyl-4-[(4-nitrophenyl)sulfonyl]-(4094-37-5)

Safety Data

• Hazardous Substances Data: 4094-37-5(Hazardous Substances Data)

Upstream product

• 100-25-4 para-dinitrobenzene 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 22865-48-1 4-nitrophenyl 4-methylphenyl sulfide 
• 100-00-5 4-chlorobenzonitrile 
• 636-98-6 p-nitrobenzene iodide 
• 17763-80-3 para-nitrophenyl triflate 
• 586-78-7 para-nitrophenyl bromide 
• 10486-08-5 sodium p-thiocresolate 
• 100-02-7 4-nitro-phenol 
• 98-59-9 p-toluenesulfonyl chloride 
• 624-31-7 4-tolyl iodide 
• 3729-43-9 Allyl 4-nitrophenyl sulfone 
• 456-27-9 4-nitrobenzenediazonium tetrafluoroborate 
• 2937-05-5 4-nitrobenzenesulfonohydrazide 

Downstream Products

• 4094-38-6 4-aminophenyl 4-methylphenyl sulfone 
• 99847-25-3 4-(4-nitrophenylsulphonyl)benzoic acid 
• 100398-04-7 (4-bromomethyl-phenyl)-(4-nitro-phenyl)-sulfone 
• 873402-78-9 1-diacetoxymethyl-4-(4-nitro-benzenesulfonyl)-benzene 
• 81981-49-9 (3aS,4R,7S,7aR)-3a,4,7,7a-Tetrahydro-1H-4,7-methano-inden-1-yl-[4-(toluene-4-sulfonyl)-phenyl]-amine 
• 32682-56-7 3,4,5-triphenyl-2-benzoylfuran 
• 1646-67-9 N-phenyl-2,3,4,5-tetraphenylpyrrole 
• 2405-97-2 tetraphenyl N-phenyl 2-oxo 4-pyrroline 
• 293758-44-8 2-methyl-5-(4-nitro-benzenesulfonyl)-benzenesulfonyl chloride 
• 138384-67-5 6-{Methyl-[4-(4-nitro-benzenesulfonyl)-benzyl]-amino}-1H-benzo[cd]indol-2-one 
• 138384-81-3 5-Methyl-6-{methyl-[4-(4-nitro-benzenesulfonyl)-benzyl]-amino}-1H-benzo[cd]indol-2-one 
• 138384-83-5 (2-Imino-5-methyl-1,2-dihydro-benzo[cd]indol-6-yl)-methyl-[4-(4-nitro-benzenesulfonyl)-benzyl]-amine 
• 859491-77-3 toluene-4-sulfonic acid-[4-(toluene-4-sulfonyl)-anilide] 

Relevant articles and documents

Visible-light-driven electron donor-acceptor complex induced sulfonylation of diazonium salts with sulfinates

This work reports an efficient sulfonylation reaction enabled by a visible-light-induced radical coupling reaction between phenyl/heterocyclic diazonium salts and sulfinates. Mechanistic experiments disclosed the formation of a versatile electron donor-acceptor (EDA) complex. This transformation is characterized by an easy operational procedure under mild conditions which avoids transition metals, ligands, catalysts, and oxidants.

TosMIC and its derivatives as versatile sulfonylating agents for the synthesis of p-toluenesulfonylarenes from aryl halides and arylboronic acids

An efficient copper(II) catalyzed sulfonyation of aryl halides has been achieved using TosMIC (p-toluenesulfonylmethyl isocyanide) as a sulfonylating agent. This newly developed sulfonylation approach provides an easy access for the synthesis of diaryl sulfones from aryl bromides, iodides and boronic acids with TosMIC under neutral conditions. This method is useful for the sulfonylation of aryl boronic acids under similar conditions. This is the first report on the sulfonylation of aryl bromides, iodides and boronic acids using TosMIC.

Mo(VI) complex catalysed synthesis of sulfonees and their modification for anti-HIV activities

An efficient method for the synthesis of sulfones has been developed using sugar derived cis-dioxo molybdenum(VI) complex as catalyst and urea hydrogen peroxide as oxygen source. Present method is highly specific for sulfide oxidation irrespective of presence of alkene and aldehyde groups in the same molecule. Synthesis of fifteen sulfones have been reported with 82–98% isolated yields and the catalyst has been reused five times without any loss in its activity. 2-(Phenylsulfonyl)aniline has been condensed with eight different aromatic aldehydes and the products are being explored for HIV-1 reverse transcriptase inhibition activities.