41831-09-8

Basic information

• Product Name: [1-(4-Methoxy-phenyl)-1-(4-trifluoromethyl-phenyl)-meth-(Z)-ylidene]-hydrazine
• Synonyms: [1-(4-Methoxy-phenyl)-1-(4-trifluoromethyl-phenyl)-meth-(Z)-ylidene]-hydrazine
• CAS NO: 41831-09-8
• Molecular Weight: 294.276
• Mol File: 41831-09-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: [1-(4-Methoxy-phenyl)-1-(4-trifluoromethyl-phenyl)-meth-(Z)-ylidene]-hydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: [1-(4-Methoxy-phenyl)-1-(4-trifluoromethyl-phenyl)-meth-(Z)-ylidene]-hydrazine(41831-09-8)
• EPA Substance Registry System: [1-(4-Methoxy-phenyl)-1-(4-trifluoromethyl-phenyl)-meth-(Z)-ylidene]-hydrazine(41831-09-8)

Safety Data

• Hazardous Substances Data: 41831-09-8(Hazardous Substances Data)

Upstream product

• 455-19-6 4-Trifluoromethylbenzaldehyde 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 87901-71-1 α-(4-methoxyphenyl)(4-trifluoromethyl)benzyl alcohol 
• 6185-76-8 (4-methoxyphenyl)(4-(trifluoromethyl)phenyl)methanone 

Relevant articles and documents

Dirhodium-Catalyzed Enantioselective B?H Bond Insertion of gem-Diaryl Carbenes: Efficient Access to gem-Diarylmethine Boranes

The scarcity of reliable methods for synthesizing chiral gem-diarylmethine borons limits their applications. Herein, we report a method for highly enantioselective dirhodium-catalyzed B?H bond insertion reactions with diaryl diazomethanes as carbene precursors. These reactions afforded chiral gem-diarylmethine borane compounds in high yield (up to 99 % yield), high activity (turnover numbers up to 14 300), high enantioselectivity (up to 99 % ee) and showed unprecedented broad functional group tolerance. The borane compounds synthesized by this method could be efficiently transformed into diaryl methanol, diaryl methyl amine, and triaryl methane derivatives with good stereospecificity. Mechanistic studies suggested that the borane adduct coordinated to the rhodium catalyst and thus interfered with decomposition of the diazomethane, and that insertion of a rhodium carbene (generated from the diaryl diazomethane) into the B?H bond was most likely the rate-determining step.