447-05-2 Usage
Description
5-Hydroxy-4-(hydroxymethyl)-6-methyl-3-pyridylmethyl dihydrogen phosphate, also known as Pyridoxol 5'-phosphate or Pyridoxol 5''-phosphate, is a vitamer of the Vitamin B6 complex (P991715). It is an essential enzyme cofactor involved in various reactions of amino acid metabolism, playing a crucial role in the proper functioning of the human body.
Uses
Used in Biochemical Processes:
5-Hydroxy-4-(hydroxymethyl)-6-methyl-3-pyridylmethyl dihydrogen phosphate is used as an enzyme cofactor for facilitating [application reason] in the field of [application type] biochemical processes. Its involvement in amino acid metabolism makes it a vital component in the conversion and utilization of amino acids within the body.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 5-hydroxy-4-(hydroxymethyl)-6-methyl-3-pyridylmethyl dihydrogen phosphate is used as an essential nutrient for [application reason] the development of supplements and medications targeting [application type] Vitamin B6 deficiency and related health issues. Its role in amino acid metabolism makes it a key ingredient in products aimed at enhancing overall health and well-being.
Used in Research and Development:
5-Hydroxy-4-(hydroxymethyl)-6-methyl-3-pyridylmethyl dihydrogen phosphate is utilized as a research compound for [application reason] studying the mechanisms of amino acid metabolism and the role of Vitamin B6 in various biological processes. This application is crucial in the field of [application type] biological and medical research, contributing to the advancement of our understanding of human health and disease.
Used in Nutritional Supplements:
In the nutritional supplement industry, 5-hydroxy-4-(hydroxymethyl)-6-methyl-3-pyridylmethyl dihydrogen phosphate is used as an active ingredient for [application reason] creating products that support [application type] optimal health and enhance amino acid metabolism. These supplements are designed to provide the necessary cofactor for various enzymatic reactions, contributing to overall well-being and health maintenance.
Used in Food Fortification:
5-Hydroxy-4-(hydroxymethyl)-6-methyl-3-pyridylmethyl dihydrogen phosphate is employed as a fortificant for [application reason] enriching the nutritional value of certain food products in the [application type] food and beverage industry. By adding this vitamer to the diet, it helps to ensure that individuals receive adequate amounts of Vitamin B6, which is essential for proper health and bodily functions.
Check Digit Verification of cas no
The CAS Registry Mumber 447-05-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,4 and 7 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 447-05:
(5*4)+(4*4)+(3*7)+(2*0)+(1*5)=62
62 % 10 = 2
So 447-05-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H12NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2,10-11H,3-4H2,1H3,(H2,12,13,14)
447-05-2Relevant articles and documents
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Morrison,Long
, p. 211,214 (1958)
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Biosynthesis of vitamin B6: Enzymatic conversion of 1-deoxy-D-xylulose- 5-phosphate to pyridoxol phosphate [14]
Cane, David E.,Du, Shoucheng,Robinson, J. Kenneth,Hsiung, Yuju,Spenser, Ian D.
, p. 7722 - 7723 (1999)
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Interconversions of different forms of vitamin B6 in tobacco plants
Huang, Shuohao,Zeng, Haibin,Zhang, Jianyun,Wei, Shu,Huang, Longquan
, p. 2124 - 2129 (2011)
There are six different vitamin B6 (VB6) forms, pyridoxal (PL), pyridoxamine (PM), pyridoxine (PN), pyridoxal 5′-phosphate (PLP), pyridoxamine 5′-phosphate (PMP), and pyridoxine 5′-phosphate (PNP), of which PLP is the active form. Although plants are a major source of VB6 in the human diet, and VB6 plays an important role in plants, the mechanisms underlying the interconversions of different VB 6 forms are not well understood. In this study, in vitro tobacco plants were grown on Murashige and Skoog (MS) basal media supplemented with 100 mg/L of PM, PL or PN and the abundance of the different B6 vitamers in leaf tissue was quantified by high performance liquid chromatography (HPLC). The total amount of VB6 was about 3.9 μg/g fresh weight of which PL, PM, PN, PLP and PMP accounted for 23%, 14%, 37%, 20% and 6%, respectively. Tobacco plants contained a trace amount of PNP. Supplementation of the culture medium with any of the non-phosphorylated vitamers resulted in an increase in total VB6 by about 10-fold, but had very little impact on the concentrations of the endogenous phosphorylated vitamers. Administration of either PM or PN increased their endogenous levels more than the levels of any other endogenous B6 vitamers. PL supplementation increased the levels of plant PN and PM significantly, but not that of PL, suggesting that efficient conversion pathways from PL to PN and PM are present in tobacco. Additionally, maintenance of a stable level of PLP in the plant is not well-correlated to changes in levels of non-phosphorylated forms.
