461-24-5

Basic information

• Product Name: 2,2,2-trifluoroethyl ethyl ether
• Synonyms: 2,2,2-trifluoroethyl ethyl ether
• CAS NO: 461-24-5
• Molecular Formula: C₄H₇F₃O
• Molecular Weight: 0
• Mol File: 461-24-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 41.7°C at 760 mmHg
• Appearance: /
• Density: 1.091g/cm³
• Vapor Pressure: 415mmHg at 25°C
• Refractive Index: 1.312
• CAS DataBase Reference: 2,2,2-trifluoroethyl ethyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-trifluoroethyl ethyl ether(461-24-5)
• EPA Substance Registry System: 2,2,2-trifluoroethyl ethyl ether(461-24-5)

Safety Data

• Hazardous Substances Data: 461-24-5(Hazardous Substances Data)

Usage

Appearance

Colorless liquid with a strong ether-like odor

Flammability

Flammable

Uses

Solvent in various chemical processes and reactions, extraction agent for separating organic compounds, reagent in the synthesis of pharmaceuticals and agrochemicals

Health hazards

Can cause irritation to the respiratory system and skin, prolonged exposure can lead to more serious health effects

Environmental hazards

Volatile organic compound that can contribute to air pollution if not properly controlled and managed.

InChI:InChI=1/C4H7F3O/c1-2-8-3-4(5,6)7/h2-3H2,1H3

Upstream product

• 64-17-5 ethanol 
• 133367-80-3 C₁₁H₁₂F₃N₃O₂ 
• 75-88-7 1,1,1-trifluoro-2-chloroethane 

Downstream Products

• 453-35-0 1,1,1-trifluoro-3-nitro-2-propanol 

Relevant articles and documents

Synthesis of trifluoroethyl ethers from 2,2,2-trifluoroethyl chloride (HCFC-133a) in high temperature aqueous medium

Treatment of 2,2,2-trifluoroethyl chloride (HCFC-133a) with alcohols (phenols) and aqueous KOH in autoclave at 240-280 C gives the corresponding 2,2,2-trifluoroethyl (2-chloro-1,1-difluoroethyl) ethers in good yields.