485403-18-7Relevant articles and documents
METHOD FOR PRODUCING FLUORINE-CONTAINING ALCOHOL
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Page/Page column 6, (2008/06/13)
PROBLEM TO BE SOLVED: To provide a method for the production of a fluorine-containing alcohol, preventing the formation of scale, suppressing side reactions, producing the alcohol in a short time in high yield and selectivity and suitable for mass-production. SOLUTION: A fluorine-containing alcohol expressed by general formula (2): Rf(A)OH (Rf is a 1-10C perfluoroalkyl group; and A is a 3-10C straight or branched-chain saturated hydrocarbon group) is produced by reacting a fluorine-containing alkyl halide expressed by general formula (1); Rf(A)X (X is a halogen atom) with an alkali metal 4-hydroxybutyrate using γ-butyrolactone as a solvent while keeping the reaction temperature to 90-130°C.