461-17-6

Basic information

• Product Name: 1-IODO-4,4,4-TRIFLUOROBUTANE
• Synonyms: 1-IODO-4,4,4-TRIFLUOROBUTANE;1,1,1-TRIFLUORO-4-IODOBUTANE;4,4,4-TRIFLUORO-1-IODOBUTANE;4,4,4-TRIFLUOROBUTYL IODIDE;4-IODO-1,1,1-TRIFLUOROBUTANE;4,4,4-Trifluorobutyl iodide~4,4,4-Trifluoro-1-iodobutane;1-Iodo-4,4,4-trifluorobutane 99%;1-Iodo-4,4,4-trifluorobutane99%
• CAS NO: 461-17-6
• Molecular Formula: C₄H₆F₃I
• Molecular Weight: 237.99
• Mol File: 461-17-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 126 °C
• Flash Point: >100°C
• Appearance: /
• Density: 1.85
• Vapor Pressure: 14.6mmHg at 25°C
• Refractive Index: 1.4326
• Storage Temp.: 2-8°C(protect from light)
• Sensitive: Light Sensitive
• BRN: 1736064
• CAS DataBase Reference: 1-IODO-4,4,4-TRIFLUOROBUTANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-IODO-4,4,4-TRIFLUOROBUTANE(461-17-6)
• EPA Substance Registry System: 1-IODO-4,4,4-TRIFLUOROBUTANE(461-17-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 23-26-36-37
• HazardClass: IRRITANT
• Hazardous Substances Data: 461-17-6(Hazardous Substances Data)

Usage

Description

1-Iodo-4,4,4-trifluorobutane is an organic compound characterized by the presence of an iodine atom and three fluorine atoms attached to a butane molecule. It is a halogenated hydrocarbon with potential applications in various industries due to its unique chemical properties.

Uses

1. Used in Pharmaceutical Industry:
1-Iodo-4,4,4-trifluorobutane is used as a chemical intermediate for the synthesis of small molecule inhibitors targeting SLC15A4, which possess anti-inflammatory activity. This application is significant in the development of new drugs to combat inflammation-related conditions.
2. Used in Chemical Synthesis:
1-Iodo-4,4,4-trifluorobutane can be utilized as a building block in the synthesis of more complex organic molecules, particularly those requiring a fluorinated or iodinated butane structure. This makes it valuable in the fields of material science and specialty chemicals.
3. Used in Research and Development:
In academic and industrial research settings, 1-Iodo-4,4,4-trifluorobutane may be employed as a reagent or starting material for exploring new chemical reactions, mechanisms, or properties of fluorinated and iodinated compounds.
4. Used in Analytical Chemistry:
1-Iodo-4,4,4-trifluorobutane could be used as a reference compound or standard in analytical techniques such as gas chromatography, mass spectrometry, or nuclear magnetic resonance (NMR) spectroscopy, where its unique structure and properties can aid in the identification and quantification of similar compounds.
5. Used in Environmental Applications:
Due to its unique chemical properties, 1-Iodo-4,4,4-trifluorobutane may have potential applications in environmental chemistry, such as in the development of new methods for the detection or remediation of pollutants.
6. Used in Material Science:
1-Iodo-4,4,4-trifluorobutane could be used in the development of new materials with specific properties, such as fluoropolymers or iodo-fluoropolymers, which may have applications in various industries, including electronics, automotive, and aerospace.

InChI:InChI=1/C4H6F3I/c5-4(6,7)2-1-3-8/h1-3H2

Upstream product

• 461-18-7 4,4,4-trifluorobutanol 
• 406-81-5 1-Bromo-4,4,4-trifluorobutane 
• 627-31-6 1,3-Diiodopropane 
• 81290-20-2 (trifluoromethyl)trimethylsilane 

Downstream Products

• 461-18-7 4,4,4-trifluorobutanol 
• 1524-26-1 4,4,4-trifluorobutene 
• 485403-18-7 4-hydroxy-butyric acid trifluorobutyl ester 
• 1373151-95-1 tert-butyl 4-({4-[5-(4,4,4-trifluorobutyl)pyridin-2-yl]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxylate 
• 639497-39-5 4-{4-[5-(4,4,4-trifluoro-butyl)-pyrazin-2-yl]benzenesulfonyl}tetrahydropyran-4-carboxylic acid tert-butyl ester 
• 639497-12-4 tert-butyl 4-({4-[5-(4,4,4-trifluorobutyl)(2-pyridyl)]phenyl}sulfonyl)-1-benzylpiperidine-4-carboxylate 
• 1303415-62-4 4-[2,4-dichloro-6-(4,4,4-trifluorobutoxy)-phenyl]-6-methyl-pyrimidin-2-ylamine 
• 1303415-64-6 2-amino-4-[2,4-dichloro-6-(4,4,4-trifluorobutoxy)phenyl]-5,7-dihydropyrrolo[3,4-d]pyrimidine-6-carboxylic acid ethylamide 
• 1046860-32-5 2-amino-4-[2,4-dichloro-6-(4,4,4-trifluorobutoxy)phenyl]-5,7-dihydropyrrolo[3,4-d]pyrimidine-6-carboxylic acid cyanomethylamide 
• 1046860-33-6 2-amino-4-[2,4-dichloro-6-(4,4,4-trifluorobutoxy)phenyl]-5,7-dihydropyrrolo[3,4-d]pyrimidine-6-carboxylic acid isopropylamide 
• 1303415-60-2 4-[2-chloro-6-(4,4,4-trifluorobutoxy)-phenyl]-6-methyl-pyrimidin-2-ylamine 
• 1303415-67-9 2-amino-4-[2,4-dichloro-6-(4,4,4-trifluorobutoxy)phenyl]-5,7-dihydropyrrolo[3,4-d]pyrimidine-6-carboxylic acid cyclopropylamide 
• 1325296-15-8 3-fluoro-4-(4,4,4-trifluorobutoxy)benzoic acid 
• 1325296-10-3 2-fluoro-4-(4,4,4-trifluorobutoxy)benzonitrile 

Relevant articles and documents

COMBINATION OF HEPATITIS B VIRUS (HBV) VACCINES AND PYRIDOPYRIMIDINE DERIVATIVES

Therapeutic combinations of hepatitis B virus (HBV) vaccines and a pyridopyrimidine derivative are described. Methods of inducing an immune response against HBV or treating an HBV-induced disease, particularly in individuals having chronic HBV infection, using the disclosed therapeutic combinations are also described. The invention provides therapeutic combinations or compositions and methods for inducing an immune response against hepatitis B viruses (HBV) infection.

TOLL LIKE RECEPTOR MODULATOR COMPOUNDS

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