5162-03-8 Usage
Description
(2-Chlorophenyl)phenyl-methanone, also known as 2-chlorobenzophenone, is an organic compound that is a metabolite of Clofedanol (C586920). It is characterized by its white to yellow crystalline powder appearance. (2-Chlorophenyl)phenyl-methanone has been investigated for its thermodynamics of formation in the inclusion complex with cyclomaltoheptaose (β-cyclodextrin) using UV-vis spectroscopy and reversed-phase liquid chromatography. Additionally, it undergoes reduction in the presence of LiAlH4 and (R)-(-)-2-(2-iso-indolinyl)butan-1-ol to produce the corresponding benzhydrols.
Uses
Used in Photocrosslinking Applications:
(2-Chlorophenyl)phenyl-methanone is used as a catalyst in the photocrosslinking of polyethylenes, which is an important process in the manufacturing of various plastic products.
Used in Pharmaceutical Synthesis:
(2-Chlorophenyl)phenyl-methanone is utilized in the synthesis of 1-(2-chlorophenyl)isoquinolin-3-yl trifluoromethanesulfonate, which is a compound with potential pharmaceutical applications.
Used in Chemical Research:
(2-Chlorophenyl)phenyl-methanone is also used in chemical research, particularly in the study of its thermodynamics of formation in inclusion complexes, which can provide insights into its potential applications in various chemical and material science fields.
Used in Reduction Reactions:
(2-Chlorophenyl)phenyl-methanone is employed in reduction reactions to afford the corresponding benzhydrols, which can be further used in the synthesis of other organic compounds with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 5162-03-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,1,6 and 2 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 5162-03:
(6*5)+(5*1)+(4*6)+(3*2)+(2*0)+(1*3)=68
68 % 10 = 8
So 5162-03-8 is a valid CAS Registry Number.
InChI:InChI=1/C13H9ClO/c14-12-9-5-4-8-11(12)13(15)10-6-2-1-3-7-10/h1-9H
5162-03-8Relevant articles and documents
Bickel,Fabens
, p. 1450 (1949)
Pd-Catalysed carbonylative Suzuki-Miyaura cross-couplings using Fe(CO)5under mild conditions: generation of a highly active, recyclable and scalable ‘Pd-Fe’ nanocatalyst
Zhu, Zhuangli,Wang, Zhenhua,Jian, Yajun,Sun, Huaming,Zhang, Guofang,Lynam, Jason M.,McElroy, C. Robert,Burden, Thomas J.,Inight, Rebecca L.,Fairlamb, Ian J. S.,Zhang, Weiqiang,Gao, Ziwei
supporting information, p. 920 - 926 (2021/02/09)
The dual function and role of iron(0) pentacarbonyl [Fe(CO)5] has been identified in gaseous CO-free carbonylative Suzuki-Miyaura cross-couplings, in which Fe(CO)5supplied COin situ, leading to the propagation of catalytically active Pd-Fe nanoparticles. Compared with typical carbonylative reaction conditions, CO gas (at high pressures), specialised exogenous ligands and inert reaction conditions were avoided. Our developed reaction conditions are mild, do not require specialised CO high pressure equipment, and exhibit wide functional group tolerance, giving a library of biaryl ketones in good yields.
Supported Palladium-Catalyzed Carbonylative Synthesis of Diaryl Ketones from Aryl Bromides and Arylboronic Acids
Xu, Tiefeng,Wang, Qi,Yang, Zeyi,Yi, Lili,Wang, Jian-Shu,Lu, Wangyang,Ying, Jun,Wu, Xiao-Feng
supporting information, p. 2027 - 2030 (2021/06/21)
A palladium supported on graphitic carbon nitride (Pd/g-C3N4) catalyzed carbonylative reaction of aryl bromides and arylboronic acids by has been developed for the construction of diaryl ketones. Using benzene-1,3,5-triyl triformate (TFBen) as the CO source, the reaction proceeded well to give various diaryl ketones in moderate to good yields.