6954-45-6

Basic information

• Product Name: (2-CHLORO-PHENYL)-PHENYL-METHANOL
• Synonyms: (2-CHLORO-PHENYL)-PHENYL-METHANOL;AURORA KA-7059;o-Chlorobenzhydrol;α-(o-Chlorophenyl)benzyl alcohol;α-Phenyl-2-chlorobenzenemethanol;Nsc37575
• CAS NO: 6954-45-6
• Molecular Formula: C₁₃H₁₁ClO
• Molecular Weight: 218.68
• Mol File: 6954-45-6.mol
• Article Data: 54

Chemical Properties

• Boiling Point: 344.1 ºC at 760 mmHg
• Flash Point: 161.9 ºC
• Appearance: /
• Density: 1.221 g/cm³
• Vapor Pressure: 2.57E-05mmHg at 25°C
• Refractive Index: 1.609
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: (2-CHLORO-PHENYL)-PHENYL-METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (2-CHLORO-PHENYL)-PHENYL-METHANOL(6954-45-6)
• EPA Substance Registry System: (2-CHLORO-PHENYL)-PHENYL-METHANOL(6954-45-6)

Safety Data

• Hazardous Substances Data: 6954-45-6(Hazardous Substances Data)

Usage

General Description

"(2-Chloro-Phenyl)-Phenyl-Methanol" is a chemical compound that consists of a phenyl and a methanol group on a phenyl ring which features a chlorine substitute at the second carbon atom. It is a derivative of benzene and an alcohol, making it an aromatic compound with hydrophilic properties. As a complex organic compound, its potential uses may vary across several industries including pharmaceuticals, synthesis of other chemicals, and materials science. However, specific details such as the chemical reaction it may undergo or the properties that it displays would be determined by the context in which it is used. Like many chemicals, it requires careful handling and usage due to possible risks associated with the chlorine group.

InChI:InChI=1/C13H11ClO/c14-12-9-5-4-8-11(12)13(15)10-6-2-1-3-7-10/h1-9,13,15H

Upstream product

• 611-17-6 1-bromomethyl-2-chlorobenzene 
• 98-80-6 phenylboronic acid 
• 89-98-5 2-chloro-benzaldehyde 
• 934-56-5 trimethyl(phenyl)stannane 
• 615-41-8 2-iodochlorobenzene 
• 100-52-7 benzaldehyde 
• 64-17-5 ethanol 
• 5162-03-8 (2-chlorophenyl)(phenyl)methanone 
• 76847-21-7 2-Chlor-1-benzol 
• 15842-76-9 (2-chloro-phenyl)-trimethyl-silane 
• 95950-06-4 1,2-bis-(2-chloro-phenyl)-1,2-diphenyl-ethane-1,2-diol 
• 108-38-3 m-xylene 
• 694-80-4 2-bromo-1-chlorobenzene 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 

Downstream Products

• 5162-03-8 (2-chlorophenyl)(phenyl)methanone 
• 16071-25-3 (S)-2-chlorobenzhydrol 
• 1509911-88-9 (E)-(3-(2-chlorophenyl)prop-1-ene-1,3-diyl)dibenzene 

Relevant articles and documents

Bio-inspired asymmetric aldehyde arylations catalyzed by rhodium-cyclodextrin self-inclusion complexes

Transition-metal catalysts are powerful tools for carbon-carbon bond-forming reactions that are difficult to achieve using native enzymes. Enzymes that exhibit inherent selectivities and reactivities through host-guest interactions have inspired widesprea

A Direct Br?nsted Acid-Catalyzed Azidation of Benzhydrols and Carbohydrates

Benzhydryl alcohols were converted into their corresponding diarylazidomethane analogues using azidotrimethylsilane (TMSN3) in the presence of a catalytic amount of a Br?nsted acid HBF4·OEt2. The azidation reactions proceeded in high yields and demonstrated excellent functional group tolerance to electron-donating and electron-withdrawing substituents. In addition, a range of unprotected functional groups including amine, amide, aldehyde and alcohol were well-tolerated. Furthermore, this methodology was successfully applied to carbohydrates for the preparation of the corresponding azide derivatives.

Iodide as a Nucleophilic Trigger in Aryne Three-Component Coupling for the Synthesis of 2-Iodobenzyl Alcohols

The synthetic potential of KI as the iodide source in aryne three-component coupling has been demonstrated using aldehydes as the third component. This mild and transition-metal-free coupling reaction allowed the straightforward synthesis of 2-iodobenzyl alcohols in moderate to good yields with good functional group compatibility. Moreover, KBr and KCl could be used as the nucleophilic trigger in this aryne multicomponent coupling (MCC) and N-methylisatin and CO2 could be used as the electrophilic third components.