538-49-8

Basic information

• Product Name: 2-(2-Phenethenyl)pyridine
• Synonyms: (E)-2-Stilbazole;2-[(E)-2-Phenylvinyl]pyridine;2-[(E)-Styryl]pyridine;2-trans-Styrylpyridine
• CAS NO: 538-49-8
• Molecular Formula: C₁₃H₁₁N
• Molecular Weight: 181.23
• EINECS: 211-934-5
• Mol File: 538-49-8.mol
• Article Data: 138

Chemical Properties

• Melting Point: 91.5°C
• Boiling Point: 304.35°C (rough estimate)
• Flash Point: 127.2°C
• Appearance: /
• Density: 1.0147
• Vapor Pressure: 0.00196mmHg at 25°C
• Refractive Index: 1.6118 (estimate)
• CAS DataBase Reference: 2-(2-Phenethenyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Phenethenyl)pyridine(538-49-8)
• EPA Substance Registry System: 2-(2-Phenethenyl)pyridine(538-49-8)

Safety Data

• Hazardous Substances Data: 538-49-8(Hazardous Substances Data)

Usage

General Description

2-(2-Phenethenyl)pyridine is a chemical compound with the formula C14H13N. It is a colorless to light yellow liquid with a strong, floral odor. 2-(2-Phenethenyl)pyridine is primarily used in the production of pharmaceuticals, flavoring agents, and fragrance ingredients. It is also commonly used as an intermediate in organic synthesis, particularly in the preparation of various pyridine derivatives. 2-(2-Phenethenyl)pyridine is considered to be relatively stable under normal conditions, but it should be handled and stored with caution due to its potential for causing irritation to the skin, eyes, and respiratory system.

InChI:InChI=1/C13H11N/c1-2-6-12(7-3-1)9-10-13-8-4-5-11-14-13/h1-11H/b10-9+

Upstream product

• 109-06-8 α-picoline 
• 100-52-7 benzaldehyde 
• 6294-62-8 2-stilbazole dibromide 
• 2637-34-5 pyridine-2-thione 
• 6783-05-7 trans-2-phenylvinylboronic acid 
• 5435-44-9 (E)-3-Ureido-but-2-enoic acid ethyl ester 
• 17881-80-0 (2-picolyl)trimethylsilane 
• 201024-81-9 C,N-diphenylnitrone 
• 1750-36-3 (E)-N-benzylidenebenzenamine 
• 2989-45-9 1-benzylidene-2-methyl-2-phenylhydrazine 
• 6852-58-0 (E)-N-benzylidene-2-methylpropan-2-amine 
• 87922-24-5 meso-1,2-dibromo1-(2-pyridyl)-2-phenylethane 
• 129760-63-0 C₉H₁₄NSi^(1-)*Li⁽¹⁺⁾ 
• 1121-60-4 pyridine-2-carbaldehyde 

Downstream Products

• 70779-18-9 6-benzhydryl-3,3,4-triphenyl-5-pyridin-2-yl-3,4-dihydro-pyran-2-one 
• 60601-60-7 2-(2-cyclohexylethyl)-piperidine hydrochloride 
• 538-49-8 (Z)-2-(2-phenylethenyl)pyridine 
• 85-02-9 benzo[f]quinoline 
• 83023-13-6 rac-2,2'-((1R,2R,3S,4S)-2,4-diphenylcyclobutane-1,3-diyl)dipyridine 
• 1205550-99-7 (E)-2-[2-[2-[5-[4-[tert-butoxycarbonyl[methyl]amino]styryl]pyridine-2-yloxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate 
• 5733-76-6 α-(2,2-diphenylvinyl)pyridine 
• 17254-30-7 (+/-)-2t-phenyl-1,2-dihydro-pyrrolo[2,1,5-de]quinolizin-2ar,3,4,5-tetracarboxylic acid tetramethyl ester 
• 17254-27-2 (+/-)-6-trans-styryl-4H-quinolizin-1,2,3,4-tetracarboxylic acid tetramethyl ester 
• 17254-31-8 (+/-)-2t-cyclohexyl-(8aξ)-1,2,6,7,8,8a-hexahydro-pyrrolo[2,1,5-de]quinolizin-2ar,3,4,5-tetracarboxylic acid tetramethyl ester 
• 17254-25-0 1,2,3,4-tetrakis-methoxycarbonyl-6-trans-styryl-quinolizinylium; tribromoide 

Relevant articles and documents

X-ray crystal structure of 2-styrylpyridine

We have crystallized the 2-styrylpyridine from the condensation reaction between the 2-methylpyridine with benzaldehyde in the formation of the model compound 2-styrylpyridine. The X-ray structure and NMR are currently reported. The main features of the structure is that it shows a localization of the double bonds rather than a delocalization of π electrons in an aromatic fashion.

A new insight into the push-pull effect of substituents via the stilbene-like model compounds

In this paper, authors report on 1-pyridyl-2-arylethenes, 1-furyl-2-arylethylenes, 1,2-diphenylpropylenes and substituted cinnamyl anilines as stilbene-like model compounds to investigate the factors dominating the push-pull effect of substituents via usi

Preparation method of alkyl/alkenyl substituted nitrogen-containing heterocyclic compound

The invention belongs to the technical field of organic synthesis, and particularly discloses a preparation method of an alkyl/alkenyl substituted nitrogen-containing heterocyclic compound, which comprises the following steps: (1) adding a 2-methyl nitrogen-containing heterocyclic compound, primary alcohol, alkali and an additive into an organic solvent, performing stirring reaction for 24 hours, and then cooling the product to room temperature; and (2) concentrating, separating and purifying the reaction liquid obtained in the step (1). The simple and effective method for preparing the alkyl/alkenyl substituted nitrogen-containing heterocyclic compound under the metal-free and ligand-free conditions is realized, the 2-methyl nitrogen-containing heterocyclic compound and the primary alcohol which are economical and easy to obtain are used as raw materials, and the alkyl/alkenyl substituted nitrogen-containing heterocyclic compound is prepared under the synergistic promotion of alkali and additives; and methyl alkylation and alkenylation reaction are carried out to generate the corresponding alkyl/alkenyl substituted nitrogen-containing heterocyclic compound. The product has high application value and can be used in the fields of spices, medicines, materials, organic synthesis and the like. The method is wide in application range, simple in process, green, simple, high in yield and suitable for popularization and application.