570391-18-3 Usage
General Description
3-Chloro-5-hydroxyBenzotrifluoride, also known as 3-Chloro-5-(trifluoromethyl)phenol, is an organic compound with the chemical formula C7H4ClF3O. It is a white crystalline solid that is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 3-Chloro-5-hydroxyBenzotrifluoride is also used as a building block in the production of specialty chemicals. It is classified as a hazardous substance and should be handled with caution due to its potential to cause skin and eye irritation. The compound is typically stored and handled in a well-ventilated area and protective equipment should be worn when working with it.
Check Digit Verification of cas no
The CAS Registry Mumber 570391-18-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,7,0,3,9 and 1 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 570391-18:
(8*5)+(7*7)+(6*0)+(5*3)+(4*9)+(3*1)+(2*1)+(1*8)=153
153 % 10 = 3
So 570391-18-3 is a valid CAS Registry Number.
InChI:InChI=1/C30F57N3/c31-4(32,7(37,38)10(43,44)13(49,50)16(55,56)19(61,62)22(67,68)25(73,74)28(79,80)81)1-88-2(5(33,34)8(39,40)11(45,46)14(51,52)17(57,58)20(63,64)23(69,70)26(75,76)29(82,83)84)90-3(89-1)6(35,36)9(41,42)12(47,48)15(53,54)18(59,60)21(65,66)24(71,72)27(77,78)30(85,86)87
570391-18-3Relevant articles and documents
Practical one-pot C-H activation/borylation/oxidation: Preparation of 3-bromo-5-methylphenol on a multigram scale
Norberg, A. Monica,Smith III, Milton R.,Maleczka Jr., Robert E.
scheme or table, p. 857 - 859 (2011/05/02)
A practical one-pot C-H activation/borylation/oxidation sequence for the generation of 3,5-disubstituted phenols is presented. Specifically, 3-bromo-5-methylphenol is prepared from 3-bromotoluene, without isolation of intermediates, on a multigram scale, and in high yield. The process proceeds under mild conditions and can be completed within one day. Georg Thieme Verlag Stuttgart - New York.
C-H activation/borylation/oxidation: A one-pot unified route to meta-substituted phenols bearing ortho-/para-directing groups
Maleczka Jr., Robert E.,Shi, Feng,Holmes, Daniel,Smith III, Milton R.
, p. 7792 - 7793 (2007/10/03)
An efficient one-pot C-H activation/borylation/oxidation protocol for the preparation of phenols is described. This method is particularly attractive for the generation of meta-substituted phenols bearing ortho-/para-directing groups, as such substrates are difficult to access by other phenol syntheses. Copyright
