610-36-6

Basic information

• Product Name: 4-Amino-2-nitrobenzoic acid
• Synonyms: 4-AMINO-2-NITROBENZOIC ACID;4-azanyl-2-nitro-benzoic acid
• CAS NO: 610-36-6
• Molecular Formula: C₇H₆N₂O₄
• Molecular Weight: 182.13
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 610-36-6.mol
• Article Data: 7

Chemical Properties

• Melting Point: 239 °C
• Boiling Point: 440.9 °C at 760 mmHg
• Flash Point: 220.4 °C
• Appearance: /
• Density: 1.568 g/cm³
• Vapor Pressure: 1.5E-08mmHg at 25°C
• Refractive Index: 1.681
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 2.84±0.25(Predicted)
• CAS DataBase Reference: 4-Amino-2-nitrobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-2-nitrobenzoic acid(610-36-6)
• EPA Substance Registry System: 4-Amino-2-nitrobenzoic acid(610-36-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 610-36-6(Hazardous Substances Data)

Usage

General Description

4-Amino-2-nitrobenzoic acid is a chemical compound with the molecular formula C7H6N2O4. It is a derivative of benzoic acid and is commonly used as an intermediate in the synthesis of pharmaceuticals and dyes. 4-Amino-2-nitrobenzoic acid is characterized by its yellow crystalline appearance and is sparingly soluble in water. 4-Amino-2-nitrobenzoic acid is known for its use in organic chemistry research as a reagent and building block for the production of various organic compounds. It is also used as a raw material in the manufacturing of drugs and other fine chemicals.

InChI:InChI=1/C7H6N2O4/c8-4-1-2-5(7(10)11)6(3-4)9(12)13/h1-3H,8H2,(H,10,11)

Upstream product

• 610-30-0 2,4-dinitrobenzoic acid 
• 64-17-5 ethanol 
• 7803-57-8 hydrazine hydrate 
• 7664-93-9 sulfuric acid 
• 21573-29-5 4-acetylamino-2-nitrobenzoic acid 
• 7647-01-0 hydrogenchloride 
• 342045-62-9 4-acetylamino-6-nitro-isophthalic acid 
• 28144-70-9 anthranilic acid amide 
• 84228-46-6 4-amino-2-nitrobenzoic acid ethyl ester 
• 2719-14-4 4-acetylamino-2-nitrotoluene 
• 121-14-2 2,4-dinitrotoluene 

Downstream Products

• 171116-84-0 N-<2-(dimethylamino)ethyl>4-(2-nitrobenzamido)2-nitrobenzamide 
• 84228-45-5 methyl-2-nitro-4-amino-benzoate 
• 54558-79-1 4-(methylthio)-2-nitrobenzoic acid 
• 74230-08-3 4-hydroxy-2-nitrobenzoic acid 
• 116529-62-5 4-iodo-2-nitro benzoic acid 
• 54056-66-5 4-cyclopropanecarbonylamino-2-nitro-benzoic acid 
• 910232-80-3 4,5,6,7-tetrahydro-benzo[b]thiophene-2-carboxylic acid [3-(6-{3-amino-4-[(2-hydroxy-ethyl)-methyl-carbamoyl]-phenylamino}-4-methyl-5-oxo-4,5-dihydro-pyrazin-2-yl)-2-methyl-phenyl]-amide 
• 910235-74-4 4,5,6,7-tetrahydro-benzo[b]thiophene-2-carboxylic acid [3-(6-{4-[(2-hydroxy-ethyl)-methyl-carbamoyl]-3-nitro-phenylamino}-4-methyl-5-oxo-4,5-dihydro-pyrazin-2-yl)-2-methyl-phenyl]-amide 
• 1072161-38-6 2'-[18F]fluoro-folic acid 
• 910233-94-2 N-(3-{6-[3-amino-4-(morpholine-4-carbonyl)-phenylamino]-4-methyl-5-oxo-4,5-dihydro-pyrazin-2-yl}-2-methyl-phenyl)-4-tert-butyl-benzamide 
• 910234-22-9 4-(tert-butyl)-N-(2-methyl-3-(1-methyl-5-((4-(morpholine-4-carbonyl)-3-nitrophenyl)amino)-6-oxo-1,6-dihydropyridin-3-yl)phenyl)benzamide 

Relevant articles and documents

The detection of glycine from the treatment of glyoxylic acid with iron(II) sulfate and ammonia in water

A glycine/(NH4)2SO4 mixture was isolated by treatment of glyoxylic acid with FeSO4 and aqNH3 in H2O. The yields of glycine were estimated by 1H NMR. Pyruvic acid was not reduced to alanine under these conditions. This method for forming glycine might have occurred prebiotically alongside the Urey-Miller arc discharge method for making amino acids because glyoxylic acid is formed by arc discharge through a N2/CO2 atmosphere and both NH3 and Fe(II) occurred in the earth's early oceans. The carboxylic acid directs the reduction of 2,4-dinitrobenzoic acid to give 2-amino-4-nitrobenzoic acid.

Optical element and compounds used in its manufacture

An optical frequency conversion element has a wave-guiding layer which consists of a χ(2) -active ferroelectric liquid crystal. The monomeric or polymeric liquid crystal material has a periodic structure which permits the so-called quasi phase matching of a guided laser beam. The period length of the structure is equal to twice the coherence length lc =?/Δβ of the material, whereby Δβ=βo (2ω)-2βo (ω), with ω=angular frequency of the fundamental wave, 0=zero-order mode and β=propagation constant of the mode.

2-ureido-benzamide derivatives

This invention is concerned with 2-ureido-benzamide compounds of the formula (1) STR1 in which R1 is H, halogen atom, (C1 -C4)alkyl, (C1 -C4)alkoxy or (C1 -C4)dialkylamino and R2 is H, halogen atom, hydroxy, nitro, (C1 -C4)alkyl, (C1 -C4)alkoxy, (C3 -C6) cycloalkylmethoxy, (C1 -C4) alkylthio, (C1 -C4) alkylsulfinyl, (C1 -C4)alkylsulfonyl or STR2 wherein j is an integer of from 0 to 2 and R3 and R4 are each independently H, (C1 -C4)alkyl, (C1 -C4)alkanoyl, (C1 -C4)alkylsulfonyl or (C1 -C4)alkylcarbamoyl, NR3 R4 can to form a pyrrolidine, piperidine, morpholine, imidazole or pyrazole ring; X is a (C3 -C15)alkyl, (C3 -C6) cycloalkyl, (C3 -C6) cycloalkylmethyl, ω-(C1 -C4) alkoxy-(C1 -C4) alkyl group or STR3 wherein k is an integer of from 1 to 4 and R5 and R6 are each independently H, Y is H or (C1 -C4)alkyl and Z is STR4 wherein m is an integer of from 0 to 4.