617-02-7

Basic information

• Product Name: O-TOLYL BENZOATE
• Synonyms: O-TOLYL BENZOATE;Benzoicacido-tolylester;o-Tolylbenzoate,99%;Benzenecarboxylic acid 2-methylphenyl ester;Benzoic acid 2-methylphenyl;Benzoic acid 2-methylphenyl ester;(2-methylphenyl) benzoate
• CAS NO: 617-02-7
• Molecular Formula: C₁₄H₁₂O₂
• Molecular Weight: 212.24
• EINECS: 210-501-8
• Mol File: 617-02-7.mol
• Article Data: 53

Chemical Properties

• Boiling Point: 170-172°C 11mm
• Flash Point: 170-172°C/11mm
• Appearance: /
• Density: 1,091 g/cm3
• Vapor Pressure: 1.23E-05mmHg at 25°C
• Refractive Index: 1.5700
• Storage Temp.: 2-8°C
• BRN: 1873222
• CAS DataBase Reference: O-TOLYL BENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: O-TOLYL BENZOATE(617-02-7)
• EPA Substance Registry System: O-TOLYL BENZOATE(617-02-7)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 617-02-7(Hazardous Substances Data)

Usage

General Description

O-Tolyl benzoate is a chemical compound that consists of a benzene ring with a benzoate group attached to the para-position of the tolyl group. It is often used as a fragrance ingredient in perfumes and other scented products due to its pleasant and fruity odor. Additionally, o-tolyl benzoate is utilized as a plasticizer in the manufacturing of plastics and resins, where it helps to improve flexibility and durability of the materials. O-TOLYL BENZOATE also has potential pharmaceutical applications, as it exhibits anti-inflammatory and anti-cancer properties, making it a subject of interest for medicinal research. Overall, o-tolyl benzoate has diverse uses in various industries, from fragrance and plastics to potential therapeutic purposes.

InChI:InChI=1/C14H12O2/c1-11-7-5-6-10-13(11)16-14(15)12-8-3-2-4-9-12/h2-10H,1H3

Upstream product

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Downstream Products

• 5326-42-1 3-methyl-4-hydroxybenzophenone 
• 73374-11-5 benzoate de bromomethyl-2 phenyle 
• 52727-93-2 benzoic acid-(4-bromo-2-methyl-phenyl ester) 
• 102242-31-9 4-hydroxy-3-methylbenzophenone benzoate 
• 60723-45-7 (1R)-(6-methoxyquinolin-4-yl)(8-vinylquinuclidin-2-yl)methyl benzoate 
• 24197-73-7 S-4-methoxyphenyl benzothioate 
• 1839-72-1 2-phenylbenzofuran 
• 404947-48-4 (4-allylhepta-1,6-dien-4-yl) benzene 
• 670221-34-8 2-(4-benzoyl-2-methylphenoxy)acetohydrazide 
• 1361296-31-2 N-oxalyl-S-(2-hydroxybenzyl)-L-cysteine 
• 80645-58-5 bromure de acetoxy-2 benzoyl-5 benzyltriphenylphosphonium 

Relevant articles and documents

Conversion of esters to thioesters under mild conditions

We report conversion of esters to thioestersviaselective C-O bond cleavage/weak C-S bond formation under transition-metal-free conditions. The method is notable for a general and practical transition-metal-free system, broad substrate scope and excellent functional group tolerance. The strategy was successfully deployed in late-stage thioesterification, site-selective cross-coupling/thioesterification/decarbonylation and easy-to-handle gram scale thioesterification. Selectivity and computational studies were performed to gain insight into the formation of weak C-S bonds by C-O bond cleavage, which contrasts with the traditional trend of nucleophilic additions to carboxylic acid derivatives.

Unexpected migration of a benzoyl group in the intramolecular Wittig reaction of o-acyloxybenzylidenephosphoranes with benzoyl chlorides: One-pot synthesis of isomeric 3-benzoyl-2-phenylbenzofurans

The reaction of o-acyloxybenzylidenetriphenylphosphoranes with substituted benzoyl chlorides in an aprotic solvent led, together with the expected 2-phenylbenzofuran, to isomeric 3-benzoyl-2-phenylbenzofuran derivatives. This result formally corresponds to intramolecular migration of the benzoyl group from the ortho oxygen atom to the ylide carbanion via cyclization and ring opening of the starting o-acyloxybenzylidenetriphenylphosphoranes.

Visible light-mediated transition metal-free esterification of amides with boronic acids

A novel strategy for visible light-mediated esterification of amides with boronic acids in air has been described. This method is characterized by mild reaction conditions and low cost owing to no need of any catalyst, which implies high potential utility in late-stage functionalization of amide drugs and materials.