626-17-5Relevant articles and documents
Catalytic activity of vanadium-substituted molybdophosphoric acid supported on titania for the vapor-phase synthesis of isophthalonitrile
Senapati,Dutta,Rana, Surjyakanta,Parida,Sahu,Sarkar
, p. 1429 - 1435 (2017)
Different wt% of vanadium-substituted molybdophosphoric acid H4PMo11VO40 loaded on titania (TiO2) are prepared by wet impregnation method. The catalytic activity of PMoV-supported titania catalyst for the vapor-phase ammoxidation of m-xylene at different temperatures is reported here. The synthesized catalysts were characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction, N2 adsorption–desorption, thermogravimetric/differential thermal analysis, temperature programmed desorption (TPD), temperature programmed reduction (TPR) scanning electron microscopy, energy-dispersive X-ray spectroscopy (EDX), and transmission electron microscopy?(TEM). FTIR studies confirmed that the Keggin structure of PMoV does not change even up to 460°C when loaded on TiO2 surface. Among all the PMoV-supported TiO2 catalysts, 1.7% PMoV/TiO2 showed excellent activity for vapor-phase ammoxidation of m-xylene with 85.4% yield of isophthalonitrile.
Visible-Light-Promoted Metal-Free Synthesis of (Hetero)Aromatic Nitriles from C(sp3)?H Bonds**
Murugesan, Kathiravan,Donabauer, Karsten,K?nig, Burkhard
supporting information, p. 2439 - 2445 (2020/12/07)
The metal-free activation of C(sp3)?H bonds to value-added products is of paramount importance in organic synthesis. We report the use of the commercially available organic dye 2,4,6-triphenylpyrylium tetrafluoroborate (TPP) for the conversion of methylarenes to the corresponding aryl nitriles via a photocatalytic process. Applying this methodology, a variety of cyanobenzenes have been synthesized in good to excellent yield under metal- and cyanide-free conditions. We demonstrate the scope of the method with over 50 examples including late-stage functionalization of drug molecules (celecoxib) and complex structures such as l-menthol, amino acids, and cholesterol derivatives. Furthermore, the presented synthetic protocol is applicable for gram-scale reactions. In addition to methylarenes, selected examples for the cyanation of aldehydes, alcohols and oximes are demonstrated as well. Detailed mechanistic investigations have been carried out using time-resolved luminescence quenching studies, control experiments, and NMR spectroscopy as well as kinetic studies, all supporting the proposed catalytic cycle.
Nickel-Catalyzed Cyanation of Aryl Thioethers
Delcaillau, Tristan,Woenckhaus-Alvarez, Adrian,Morandi, Bill
supporting information, p. 7018 - 7022 (2021/09/13)
A nickel-catalyzed cyanation of aryl thioethers using Zn(CN)2 as a cyanide source has been developed to access functionalized aryl nitriles. The ligand dcype (1,2-bis(dicyclohexylphosphino)ethane) in combination with the base KOAc (potassium acetate) is essential for achieving this transformation efficiently. This reaction involves both a C-S bond activation and a C-C bond formation. The scalability, low catalyst and reagents loadings, and high functional group tolerance have enabled both late-stage derivatization and polymer recycling, demonstrating the reaction's utility across organic chemistry.