6269-31-4

Basic information

• Product Name: 2-[(4-chlorophenyl)sulfonyl]benzene-1,4-diol
• Synonyms: 1,4-benzenediol, 2-[(4-chlorophenyl)sulfonyl]-; 2-(4-Chloro-benzenesulfonyl)-benzene-1,4-diol
• CAS NO: 6269-31-4
• Molecular Formula: C₁₂H₉ClO₄S
• Molecular Weight: 284.7155
• Mol File: 6269-31-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 531.7°C at 760 mmHg
• Flash Point: 275.4°C
• Density: 1.525g/cm³
• Vapor Pressure: 6.36E-12mmHg at 25°C
• Refractive Index: 1.651
• CAS DataBase Reference: 2-[(4-chlorophenyl)sulfonyl]benzene-1,4-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(4-chlorophenyl)sulfonyl]benzene-1,4-diol(6269-31-4)
• EPA Substance Registry System: 2-[(4-chlorophenyl)sulfonyl]benzene-1,4-diol(6269-31-4)

Safety Data

• Hazardous Substances Data: 6269-31-4(Hazardous Substances Data)

Usage

Type

Chemical compound
Used in the pharmaceutical industry

Classification

Non-steroidal anti-inflammatory drug (NSAID)
Commonly used for pain and inflammation

Properties

Anti-inflammatory
Analgesic (pain-relieving)
Antipyretic (fever-reducing)

Mechanism of action

Inhibition of prostaglandin production
Prostaglandins are responsible for inflammation and pain

Potential anti-cancer properties

Inhibits the growth of certain cancer cells

Neurodegenerative disorder treatment potential

Shown potential in treating Parkinson's disease

Ongoing research

Focused on exploring therapeutic properties and applications in the medical field

Upstream product

• 100-03-8 4-chlorobenzenesulfinic acid 
• 123-31-9 hydroquinone 
• 56621-48-8 1-(4-hydroxyphenyl)piperazine 
• 14752-66-0 sodium p-chlorobenzenesulphinate 
• 108-95-2 phenol 
• 150-76-5 4-methoxy-phenol 
• 106-51-4 p-benzoquinone 
• 98-60-2 4-chlorobenzenesulfonyl chloride 

Relevant articles and documents

Electrochemical-In-Situ-Oxidative Sulfonylation of Phenols with Sulfinic Acids as an Access to Sulfonylated Hydroquinones

The electrochemical in-situ oxidative sulfonylation of phenols with sulfinic acids access to sulfonylated hydroquinones has been developed. A series of sulfonylated hydroquinones were prepared under mild mediator-, catalyst- and exogenous-oxidant-free con

Ammonium iodide-promoted unprecedented arylsulfonylation of quinone with sodium arylsulfinates

A novel ammonium iodide-promoted arylsulfonylation of quinones with sodium arylsulfinates has been explored. This reaction proceeded smoothly through unique nucleophilic addition reaction and produced the arylsulfonylation products in moderate to good yields. The reactions proceeded efficiently over a broad range of substrates with good regioselectivity and functional group tolerance.

Different strategies in electrochemical synthesis of new mono and di-substituted hydroquinone and benzoquinone

Electrochemical syntheses of 2-indolyl-5-arylsulfonyl-p-benzoquinone derivatives were carried out in two successive oxidation steps. The first involves the oxidation of hydroquinone, 4-(piperazin-1-yl) phenol) and 1-(4-(4-hydroxyphenyl) piperazin-1-yl) et