640279-63-6

Basic information

• Product Name: O-[(2S)-hydroxy-(3R)-3-nitro-4-phenylbutanoyl]-(1'R,2'S,5'R)-8'-phenylmenthol
• Synonyms: O-[(2S)-hydroxy-(3R)-3-nitro-4-phenylbutanoyl]-(1'R,2'S,5'R)-8'-phenylmenthol
• CAS NO: 640279-63-6
• Molecular Weight: 439.552
• Mol File: 640279-63-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: O-[(2S)-hydroxy-(3R)-3-nitro-4-phenylbutanoyl]-(1'R,2'S,5'R)-8'-phenylmenthol(CAS DataBase Reference)
• NIST Chemistry Reference: O-[(2S)-hydroxy-(3R)-3-nitro-4-phenylbutanoyl]-(1'R,2'S,5'R)-8'-phenylmenthol(640279-63-6)
• EPA Substance Registry System: O-[(2S)-hydroxy-(3R)-3-nitro-4-phenylbutanoyl]-(1'R,2'S,5'R)-8'-phenylmenthol(640279-63-6)

Safety Data

• Hazardous Substances Data: 640279-63-6(Hazardous Substances Data)

Upstream product

• 6125-24-2 2-Phenylnitroethane 
• 84312-20-9 (1R,3R,4S)-8-phenylmenthyl glyoxylate 

Downstream Products

• 65322-89-6 methyl (2S)-2-(((2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl)amino)-4-methylpentanoate 
• 685508-06-9 O-[(3R)-tert-butoxycarbonylamino-(2S)-hydroxy-2,3-isopropylidene-4-phenylbutanoyl]-(1'R,2'S,5'R)-8'-phenylmenthol 
• 640279-64-7 O-[(3R)-tert-butoxycarbonylamino-(2S)-hydroxy-4-phenylbutanoyl]-(1'R,2'S,5'R)-8'-phenylmenthol 
• 685508-11-6 [(3R)-tert-butoxycarbonylamino-(2S)-hydroxy-2,3-isopropylidene-4-phenylbutanoyl]-L-leucine methyl ester 
• 139397-07-2 (4R,5S)-4-benzyl-3-[(tert-butoxy)carbonyl]-2,2-dimethyl-1,3-oxazolidine-5-carboxylic acid 
• 65391-42-6 Bestatin hydrochloride 

Relevant articles and documents

Highly diastereoselective Henry reaction of nitro compounds with chiral derivatives of glyoxylic acid

N-Glyoxyloyl-(2R)-bornane-10,2-sultam and (1R)-8-phenylmenthyl glyoxylate react stereoselectively with simple nitro compounds giving diastereoisomeric nitroalcohols with high asymmetric induction. N-Glyoxyloyl-(2R)-bornane-10,2- sultam 1a is shown to be a

Synthesis of (-)-bestatin and the Taxotere side-chain via nitroaldol reaction of (1R)-8-phenylmenthyl glyoxylate

The nitroaldol reaction of (1R)-8-phenylmenthyl glyoxylate 6 with 1-nitro-2-phenylethane or with phenylnitromethane led stereoselectively to adducts 4 and 12, which where then transformed into (-)-bestatin hydrochloride and the Taxotere side-chain in over