66648-44-0

Basic information

• Product Name: N-FeruloyloctopaMine
• Synonyms: N-FeruloyloctopaMine;trans-N-Feruloyl octopamine;OctopaMine, N-feruloyl-;N-feruloyl
• CAS NO: 66648-44-0
• Molecular Formula: C₁₈H₁₉NO₅
• Molecular Weight: 329.34716
• Mol File: 66648-44-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-FeruloyloctopaMine(CAS DataBase Reference)
• NIST Chemistry Reference: N-FeruloyloctopaMine(66648-44-0)
• EPA Substance Registry System: N-FeruloyloctopaMine(66648-44-0)

Safety Data

• Hazardous Substances Data: 66648-44-0(Hazardous Substances Data)

Usage

General Description

N-Feruloyloctopamine is a chemical compound that belongs to the class of ferulic acid derivatives. It is a naturally occurring compound found in various plants such as citrus fruits, vegetables, and cereals. N-Feruloyloctopamine has been studied for its potential health benefits, including its antioxidant and anti-inflammatory properties. It has also been investigated for its potential role in promoting cardiovascular health and improving blood circulation. Additionally, N-Feruloyloctopamine has been studied for its antimicrobial and anti-cancer properties, showing potential as a natural compound for therapeutic applications. Overall, N-Feruloyloctopamine has shown promise as a bioactive compound with various potential health benefits, making it a subject of ongoing research and interest in the field of natural medicine and nutrition.

Upstream product

• 121-33-5 vanillin 
• 104-14-3 octopamine 
• 1135-24-6 (E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid 
• 56254-05-8 ferulic acid N-hydroxysuccinimidyl ester 

Downstream Products

• 66648-48-4 triacetyl N-trans-feruloyl octopamine 

Relevant articles and documents

Synthesis and structure-activity relationships and effects of phenylpropanoid amides of octopamine and dopamine on tyrosinase inhibition and antioxidation

Phenylpropanoid amides of octopamine (OA) 1a-1e and dopamine (DA) 2a-2e were synthesised and the structure-activity relationships (SARs) for antioxidant and tyrosinase inhibition activities were analysed. Among synthesised compounds, 2c, which contains two catechol moieties, exhibited the most DPPH radical-scavenging activity (EC50 = 16.2 ± 2.4 μM), and 1d exhibited significant tyrosinase inhibitory activity (IC50 = 5.3 ± 1.8 μM). Interestingly, with the same acid moiety, OA derivatives showed more inhibitory effect on tyrosinase than did compounds derived from DA, whereas DA derivatives were found to have higher antioxidant activity than compounds derived from OA. The relationship between their structures and their potencies, demonstrated in the current study, will be useful for the design of optimal agents.