669080-86-8

Basic information

• Product Name: 5-[N-(3',5'-BISTRIFLUOROMETHYLBENZYL)AMINO]-2-METHYLTETRAZOLE
• Synonyms: 5-[N-(3',5'-BISTRIFLUOROMETHYLBENZYL)AMINO]-2-METHYLTETRAZOLE;5-[N-(3';5'-BistrifluoroMethylbenzyl)aMino]-2-Methyltetrazole
• CAS NO: 669080-86-8
• Molecular Formula: C₁₁H₉F₆N₅
• Molecular Weight: 325.2130792
• Mol File: 669080-86-8.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-[N-(3',5'-BISTRIFLUOROMETHYLBENZYL)AMINO]-2-METHYLTETRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[N-(3',5'-BISTRIFLUOROMETHYLBENZYL)AMINO]-2-METHYLTETRAZOLE(669080-86-8)
• EPA Substance Registry System: 5-[N-(3',5'-BISTRIFLUOROMETHYLBENZYL)AMINO]-2-METHYLTETRAZOLE(669080-86-8)

Safety Data

• Hazardous Substances Data: 669080-86-8(Hazardous Substances Data)

Usage

General Description

5-[N-(3',5'-BISTRIFLUOROMETHYLBENZYL)AMINO]-2-METHYLTETRAZOLE is a chemical compound that belongs to the tetrazole class of organic compounds. It is characterized by the presence of a tetrazole ring, which is a five-membered ring containing four nitrogen atoms and one carbon atom. 5-[N-(3',5'-BISTRIFLUOROMETHYLBENZYL)AMINO]-2-METHYLTETRAZOLE also contains an amino group attached to a benzyl group, which in turn is substituted with a trifluoromethyl group. The presence of these functional groups gives 5-[N-(3',5'-BISTRIFLUOROMETHYLBENZYL)AMINO]-2-METHYLTETRAZOLE unique chemical properties and potential applications in medicinal chemistry, particularly in the development of pharmaceuticals and bioactive compounds.

Upstream product

• 6154-04-7 2-methyl-2H-tetrazole-5-amine 
• 401-95-6 3,5-Bis(trifluoromethyl)benzaldehyde 
• 5422-44-6 1-methyl-5-amino-1H-tetrazole 
• 956631-60-0 C₁₁H₇F₆N₅ 

Downstream Products

• 880103-63-9 C₂₆H₂₅F₉N₆O₂ 
• 943551-29-9 [3,5-bis(trifluoromethyl)benzyl](2-chloro-5-trifluoromethylpyridin-3-ylmethyl)(2-methyl-2H-tetrazol-5-yl)amine 
• 1026137-15-4 [3,5-bis(trifluoromethyl)benzyl](2-chloro-7-fluoroquinolin-3-ylmethyl)(2-methyl-2H-tetrazol-5-yl)amine 
• 888738-14-5 N-(2-bromo-5-(trifluoromethyl)benzyl)-N-(3,5-bis(trifluoromethyl)benzyl)-2-methyl-2H-tetrazol-5-amine 
• 888738-22-5 (3,5-bis-trifluoromethyl-benzyl)-(2-bromo-6-trifluoromethyl-pyridin-3-ylmethyl)-(2-methyl-2H-tetrazol-5-yl)-amine 
• 957216-46-5 (3-{[(3,5-bistrifluoromethylbenzyl)(2-methyl-2H-tetrazol-5-yl)amino]methyl}pyridin-2-yl)cyclopentylmethylethylamine 

Relevant articles and documents

Design, synthesis and biological evaluation of n,n-substituted amine derivatives as cholesteryl ester transfer protein inhibitors

N,N-Substituted amine derivatives were designed by utilizing a bioisosterism strategy. Consequently, twenty-two compounds were synthesized and evaluated for their inhibitory activity against CETP. Structure-activity relationship (SAR) studies indicate tha

HETEROCYCLIC DERIVATIVES AS CETP INHIBITORS

The present invention provides a compound of formula (I), said compound is an inhibitor of CETP, and thus can be employed for the treatment of a disorder or disease mediated by CETP or responsive to the inhibition of CETP.

BICYCLIC DERIVATIVES AS CETP INHIBITORS

The present invention relates to novel compounds of formula (I): or a pharmaceutical composition thereof, with all the variables being defined in the text. The present invention further relates to the use of the compounds herein for treatment of or delay