73442-13-4

Basic information

• Product Name: 3-(5-Phenyloxazol-4-yl)propylisocyanid
• CAS NO: 73442-13-4
• Molecular Weight: 212.251
• Mol File: 73442-13-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(5-Phenyloxazol-4-yl)propylisocyanid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(5-Phenyloxazol-4-yl)propylisocyanid(73442-13-4)
• EPA Substance Registry System: 3-(5-Phenyloxazol-4-yl)propylisocyanid(73442-13-4)

Safety Data

• Hazardous Substances Data: 73442-13-4(Hazardous Substances Data)

Upstream product

• 50326-52-8 NN'-diformyl-1,4-diaminobutane 
• 1696-17-9 N,N-diethylbenzamide 
• 929-25-9 1,4-Butylendiisocyanid 

Relevant articles and documents

Synthesis with α-Metalated Isocyanides, XLIII. - Experiments with Lithiated α,ω-Alkylene Diisocyanides

1,2-Ethylene diisocyanide (4a) reacts with two equivalents of butyllithium (-100 deg C) to give 1,1-dilithio-1,2-ethylene diisocyanide (7) which with ketones yields the oxazines 11. - 1,3-Propylene diisocyanide (4b) reacts with one equivalent butyllithium (-70 deg C) to furnish 1-lithio-1,3-propylene diisocyanide (12) which cyclizes to afford 3-lithio-1-pyrrolin-3-yl isocyanide (14).With ketones, chlorotrimethylsilane, and epoxides 14 furnishes the compounds 17-19 and 21. - 1,4-Butylene diisocyanide (4c) reacts (-100 deg C) with one equivalent butyllithium to give 1-lithio-1,4-butylene diisocyanide (23), and with two equivalents to give 1,4-dilithio-1,4-butylene diisocyanide (28).Both compounds are thermolabile, but can be trapped by electrophils which react below -60 deg C.