748756-00-5

Basic information

• Product Name: (R)-2-((2R,6S)-1-Methyl-6-phenethyl-piperidin-2-yl)-1-phenyl-ethanol
• Synonyms: (R)-2-((2R,6S)-1-Methyl-6-phenethyl-piperidin-2-yl)-1-phenyl-ethanol
• CAS NO: 748756-00-5
• Molecular Weight: 323.478
• Mol File: 748756-00-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-2-((2R,6S)-1-Methyl-6-phenethyl-piperidin-2-yl)-1-phenyl-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-((2R,6S)-1-Methyl-6-phenethyl-piperidin-2-yl)-1-phenyl-ethanol(748756-00-5)
• EPA Substance Registry System: (R)-2-((2R,6S)-1-Methyl-6-phenethyl-piperidin-2-yl)-1-phenyl-ethanol(748756-00-5)

Safety Data

• Hazardous Substances Data: 748756-00-5(Hazardous Substances Data)

Upstream product

• 134-63-4 Lobeline hydrochloride 
• 946434-65-7 C₂₄H₂₉NO₃ 
• 90-69-7 lobeline 
• 758717-83-8 (R)-2-[(2R,6S)-1-Methyl-6-((E)-styryl)-piperidin-2-yl]-1-phenyl-ethanol 
• 324078-36-6 cis-2S,6R-N-methyl-6-phenacyl-2-trans-styrylpiperidine 

Relevant articles and documents

Efficient enantioselective synthesis of piperidines through catalytic asymmetric ring-opening/cross-metathesis reactions

Mo the better! Chiral Mo complexes promote highly efficient asymmetric ring-opening/cross-metathesis reactions that afford functionalized piperidines in high E:Z selectivity and enantiomeric purity (see scheme for example; TBS = tert-butyldimethylsilyl).

Lobeline: Structure-affinity investigation of nicotinic acetylcholinergic receptor binding

(-)Lobeline (1) and (-)nicotine (2) bind at neuronal nicotinic cholinergic (nACh) receptors with high affinity (K1 = 4 and 2 nM, respectively). Previous attempts to determine whether lobeline fits the currently accepted nicotinic pharmacophore