7576-08-1

Basic information

• Product Name: Benzeneacetonitrile, a-[2-(dimethylamino)propyl]-a-phenyl-, (S)-
• CAS NO: 7576-08-1
• Molecular Formula: C19H22N2
• Molecular Weight: 278.397
• Mol File: 7576-08-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzeneacetonitrile, a-[2-(dimethylamino)propyl]-a-phenyl-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetonitrile, a-[2-(dimethylamino)propyl]-a-phenyl-, (S)-(7576-08-1)
• EPA Substance Registry System: Benzeneacetonitrile, a-[2-(dimethylamino)propyl]-a-phenyl-, (S)-(7576-08-1)

Safety Data

• Hazardous Substances Data: 7576-08-1(Hazardous Substances Data)

Upstream product

• 40916-65-2 (S)-2-(dimethylamino)-1-propanol 
• 86-29-3 Diphenylacetonitrile 
• 57496-00-1 (R)-2-Chloro-N,N-dimethylpropylamine 
• 53847-23-7 diphenylcyanomethylsodium 
• 125-79-1 (R,S)-2,2-diphenyl-4-dimethylaminopentanenitrile 
• 57496-01-2 (R)-(-)-1-dimethylamino-2-chloropropane hydrochloride 

Downstream Products

• 5653-80-5 (S)-methadone 
• 110050-37-8 (S)-4-dimethylamino-2.2-diphenyl-valeric acid ethyl ester 
• 87246-93-3 (S)-(+)-1,5-dimethyl-3,3-diphenyl-2-pyrrolidone 
• 106293-51-0 (S)-(+)-2-imino-1,5-dimethyl-3,3-diphenylpyrrolidine 
• 31161-17-8 (S)-(-)-2-ethyl-1,5-dimethyl-3,3-diphenylpyrrolinium perchlorate 
• 43033-72-3 levomethadyl acetate hydrochloride 
• 14019-10-4 (3S,6S)-Methadol 
• 15284-15-8 (+)-Methadone hydrochloride 
• 106293-48-5 (S)-(-)-4-(N-carbomethoxy-N-methyl)-2,2-diphenylvaleronitrile 

Relevant articles and documents

SYNTHESIS OF LEVOMETHADONE HYDROCHLORIDE OR DEXTROMETHADONE HYDROCHLORIDE AND METHODS FOR USE THEREOF

Highly efficient methods for synthesis of levomethadone hydrochloride or dextromethadone hydrochloride are provided starting from D-alanine, or L-alanine, respectively, with retention of configuration. Methods for treating a subject are provided comprising administering a composition comprising an effective amount of levomethadone hydrochloride having not more than 10 ppm dextromethadone.

Process for the preparation of optically active methadones in high enantiomeric purity

PCT No. PCT/GB97/01441 Sec. 371 Date Apr. 9, 1999 Sec. 102(e) Date Apr. 9, 1999 PCT Filed May 27, 1997 PCT Pub. No. WO97/45551 PCT Pub. Date Dec. 4, 1997A method of preparing optically active methadones comprises an enzymatic process for the resolution of 1-dialkyl-amino-2-propanol and conversion of the enantiomers to the optically active methadones in high enantiomeric purity.