75768-66-0Relevant articles and documents
Aminoacid-derivatized Cu (II) complexes: Synthesis, DNA interactions and in vitro cytotoxicity
Singh, Rinky,Devi, P. Rama,Jana, Sharmita S.,Devkar, Ranjitsinh V.,Chakraborty, Debjani
, p. 157 - 169 (2017/09/30)
Two different series of copper complexes, [Cu(MFL)(FcAA)H2O] (C1-C4) and [Cu(MFL) (BzAA)H2O] (C5-C8), where FcAA = ferrocenyl amino acid mannich base conjugates and BzAA = benzaldehyde amino acid mannich base conjugates have been syn
Structure-Activity Relationships of the Peptide Kappa Opioid Receptor Antagonist Zyklophin
Joshi, Anand A.,Murray, Thomas F.,Aldrich, Jane V.
, p. 8783 - 8795 (2015/12/08)
The dynorphin (Dyn) A analogue zyklophin ([N-benzyl-Tyr1-cyclo(d-Asp5,Dap8)]dynorphin A(1-11)NH2) is a kappa opioid receptor (KOR)-selective antagonist in vitro, is active in vivo, and antagonizes KOR in the CNS
The effects of C-terminal modifications on the opioid activity of [N-benzylTyr1]dynorphin A-(1-11) analogues
Patkar, Kshitij A.,Murray, Thomas F.,Aldrich, Jane V.
supporting information; experimental part, p. 6814 - 6821 (2010/03/31)
Structural modifications affecting the efficacy of analogues of the endogenous opioid peptide dynorphin (Dyn) A have focused on the N-terminal "message" sequence based on the "message-address" concept. To test the hypothesis that changes in the C-terminal