771-69-7Relevant articles and documents
Method for pipeline continuous fluorination with fluorine salt as fluorine source
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Paragraph 0056-0061; 0094-0096, (2021/10/27)
The method comprises the following steps: dissolving a fluorine salt in an aqueous polar aprotic solvent as reaction liquid A, dissolving an aryl (heterocyclic) chloride in a polar aprotic solvent as reaction liquid B, and reacting a polar aprotic solvent in the reaction liquid A with a polar aprotic solvent of the reaction liquid B. The reaction medium consisting of the preheated reaction liquid A and the preheated reaction liquid B enters the reaction coil for a fluorination reaction, and the resulting product from the reaction coil is subjected to post-treatment to obtain the product. The method has the characteristics of no need of adding a phase transfer catalyst, continuous production, low production cost and the like.
Novel manufacturing method of fluoro-aryl compounds and derivatives thereof
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Paragraph 0201-0205; 0232-0236, (2020/01/25)
The invention relates to a novel method of manufacturing fluoro-aryl compounds and derivatives thereof, in particular, fluorobenzene and derivatives thereof. The production environment of the manufacturing method is environmentally friendly. The shortages of a conventional method are overcome through a simple and beneficial mode. Compared with the prior art, the provided method is more effective,more environmentally friendly, and more energy saving. The method is used to produce core fluorinated aromatic compounds, preferably, core fluorinated fluorobenzene. On one aspect, the invention provides a method, which is advantages in industry and uses HF and a halogenated benzene precursor to prepare fluorobenzene and hydrogen halide. Moreover, the invention provides chlorobenzene as the primary raw material to prepare fluorobenzene, which is an important material in industry, and a beneficial, unexpected and simple application of chlorobenzene. In the prior art, the provided application ofchlorobenzene is unknown.
Preparation method of 2, 3, 4-trifluoronitrobenzene
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Paragraph 0012; 0014; 0015, (2019/05/15)
The invention belongs to the field of organic synthesis, and particularly relates to a preparation method of 2, 3, 4-trifluoronitrobenzene. The method comprises the following steps: reacting 2,6-dichlorofluorobenzene as a raw material with HNO3/H2SO4 so as to obtain 2, 6-dichloro-3-nitrofluorobenzene, and then reacting the 2, 6-dichloro-3-nitrofluorobenzene with anhydrous potassium fluoride to obtain the 2, 3, 4-trifluoronitrobenzene. The method disclosed by the invention is high in yield, simple in synthesis and suitable for industrial production.