84355-10-2

Basic information

• Product Name: Benzene, 1,4-dimethoxy-2-(trifluoromethyl)-
• Synonyms: 2-trifluoro-1,4-dimethoxybenzene;2-Trifluoromethyl-1,4-dimethoxybenzene;1,4-dimethoxy-2-trifluoromethylbenzene
• CAS NO: 84355-10-2
• Molecular Formula: C9H9F3O2
• Molecular Weight: 206.164
• Mol File: 84355-10-2.mol
• Article Data: 33

Chemical Properties

• Boiling Point: 227.6±40.0 °C(Predicted)
• Density: 1.205±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzene, 1,4-dimethoxy-2-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,4-dimethoxy-2-(trifluoromethyl)-(84355-10-2)
• EPA Substance Registry System: Benzene, 1,4-dimethoxy-2-(trifluoromethyl)-(84355-10-2)

Safety Data

• Hazardous Substances Data: 84355-10-2(Hazardous Substances Data)

Upstream product

• 421-83-0 trifluoromethane sulfonyl chloride 
• 150-78-7 1,4-dimethoxybezene 
• 80783-62-6 N-Trifluoromethyl-N-nitrosobenzenesulfonamide 
• 99964-09-7 N-trifluoromethyl-N-nitrosotrifluoromethanesulfon-amide 
• 107099-99-0 2,5-dimethoxyphenylboronic acid 
• 129946-88-9 Umemoto's reagent 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 2926-29-6 Langlois reagent 
• 407-25-0 trifluoroacetic anhydride 
• 75-63-8 Bromotrifluoromethane 
• 2314-97-8 iodotrifluoromethane 
• 1961266-44-3 2,8-difluoro-5-(trifluoromethyl)-5H-dibenzo[b,d]thiophen-5-ium trifluoromethanesulfonate 
• 127271-65-2 1-fluoro-4-methoxy-2-(trifluromethyl)benzene 
• 124-41-4 sodium methylate 

Relevant articles and documents

Recyclable alkylated Ru(bpy)32+ complex as a visible-light photoredox catalyst for perfluoroalkylation

A recyclable Ruthenium tris [4,4′-bis (dinonylmethyl)-2,2′-bipyridine] (Ru[(DNM)2bpy]32+) photocatalyst (PC) was synthesized. Hexane-phase-selective solubility allowed its simple and efficient separation from reaction products via solvent extraction. The excellent catalytic activity and recoverability were demonstrated in batch and flow perfluoroalkylation reactions of coumarin under visible-light irradiation. High reaction rates and easy reusability of the catalyst make this approach attractive for large-scale applications.

Regioselective C-H Trifluoromethylation of Aromatic Compounds by Inclusion in Cyclodextrins

A regioselective radical C-H trifluoromethylation of aromatic compounds was developed using cyclodextrins (CDs) as additives. The C-H trifluoromethylation proceeded with high regioselectivity to afford the product in good yield, even on the gram scale. In the presence of CDs, some substrates underwent a single trifluoromethylation selectively, whereas mixtures of single- and double-trifluoromethylated products were formed in the absence of the CD. 1H NMR experiments indicated that the regioselectivity was controlled by the inclusion of a substrate inside the CD cavity.

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