864387-30-4

Basic information

• Product Name: methyl 2-(5-bromopentanoylamino)-6-chlorobenzoate
• Synonyms: methyl 2-(5-bromopentanoylamino)-6-chlorobenzoate
• CAS NO: 864387-30-4
• Molecular Weight: 348.624
• Mol File: 864387-30-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 2-(5-bromopentanoylamino)-6-chlorobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(5-bromopentanoylamino)-6-chlorobenzoate(864387-30-4)
• EPA Substance Registry System: methyl 2-(5-bromopentanoylamino)-6-chlorobenzoate(864387-30-4)

Safety Data

• Hazardous Substances Data: 864387-30-4(Hazardous Substances Data)

Upstream product

• 4509-90-4 5-bromovaleroyl chloride 
• 41632-04-6 methyl 6-chloroanthranilate 

Downstream Products

• 864387-31-5 methyl 2-chloro-6-[5-(4-quinolin-2-ylpiperazin-1-yl)pentanoylamino]benzoate 

Relevant articles and documents

PYRIMIDINE DERIVATIVE

This invention provides pyrimidine derivatives represented by a formula, in the formula, ring A stands for carbocyclic group or heterocyclic group, X 1 stands for hydrogen, lower alkyl, amino, etc., X 2 stands for hydrogen or lower alkyl, Y stands for a direct bond or sulfur or nitrogen, n stands for an integer of 0 - 4, and Ar stands for a group of the following formula, or a salt thereof, which concurrently exhibit 5-HT 1A agonistic activity and 5-HT 3 antagonistic activity and are useful for therapy and treatments of diseases such as IBS. The invention furthermore provides a therapeutic method of IBS, characterized by having 5-HT 1A agonistic activity and 5-HT 3 antagonistic activity work simultaneously and cooperatively in vivo, which comprises either administering 5-HT 3 antagonistic agent which concurrently exhibits 5-HT 1A agonistic activity, or administering 5-HT 1A agonistic agent and 5-HT 3 antagonistic agent simultaneously, in sequence or at an interval.