869637-58-1

Basic information

• Product Name: (2-hydroxyphenyl)( pyrimido[1,2-b]indazol-3-yl)methanone
• Synonyms: (2-hydroxyphenyl)( pyrimido[1,2-b]indazol-3-yl)methanone
• CAS NO: 869637-58-1
• Molecular Weight: 289.293
• Mol File: 869637-58-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2-hydroxyphenyl)( pyrimido[1,2-b]indazol-3-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-hydroxyphenyl)( pyrimido[1,2-b]indazol-3-yl)methanone(869637-58-1)
• EPA Substance Registry System: (2-hydroxyphenyl)( pyrimido[1,2-b]indazol-3-yl)methanone(869637-58-1)

Safety Data

• Hazardous Substances Data: 869637-58-1(Hazardous Substances Data)

Upstream product

• 874-05-5 3-aminoindazole 
• 17422-74-1 3-Formylchromone 

Relevant articles and documents

An approach towards the synthesis of novel fused nitrogen tricyclic heterocyclic scaffolds: Via GBB reaction

A concise and efficient one-pot synthesis of novel N-fused tricyclic derivatives has been developed by using the Groebke-Blackburn-Bienaymé (GBB) reaction, which involved the reaction of 3-amino-1H-indazoles, aldehydes and isonitriles to afford 2-aryl-5H-imidazo[1,2-b]indazol-3-amine derivatives via a formal [4 + 1] cycloaddition reaction. Furthermore, we describe an unprecedented reaction of chromone-3-carboxaldehydes with 3-amino-1H-indazoles to afford (2-hydroxyphenyl)(pyrimido[1,2-b]indazol-3-yl)methanones in one-pot at ambient temperature. This protocol features a robust method for the one-step construction of new tricyclic rings, column chromatography free methods with a clean reaction profile, high yields, operational simplicity and it tolerates a diverse collection of reactants.