910303-23-0

Basic information

• Product Name: {2-[4-(3-amino-propoxy)-3-iodo-phenyl]-ethyl}-carbamic acid tert-butyl ester
• Synonyms: {2-[4-(3-amino-propoxy)-3-iodo-phenyl]-ethyl}-carbamic acid tert-butyl ester
• CAS NO: 910303-23-0
• Molecular Weight: 420.291
• Mol File: 910303-23-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {2-[4-(3-amino-propoxy)-3-iodo-phenyl]-ethyl}-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {2-[4-(3-amino-propoxy)-3-iodo-phenyl]-ethyl}-carbamic acid tert-butyl ester(910303-23-0)
• EPA Substance Registry System: {2-[4-(3-amino-propoxy)-3-iodo-phenyl]-ethyl}-carbamic acid tert-butyl ester(910303-23-0)

Safety Data

• Hazardous Substances Data: 910303-23-0(Hazardous Substances Data)

Upstream product

• 3953-14-8 2-(3-iodo-4-hydroxyphenyl)ethylamine 
• 51-67-2 tyrosamine 
• 788824-50-0 [2-(4-hydroxy-3-iodo-phenyl)-ethyl]-carbamic acid tert-butyl ester 
• 910303-21-8 (2-{4-[3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-prpopoxy]-3-iodo-phenyl}-ethyl)-carbamic acid tert-butyl ester 

Downstream Products

• 910303-25-2 (2-{4-[3-(acridin-9-ylamino)-propoxy]-3-iodo-phenyl}-ethyl)-carbamic acid tert-butyl ester 

Relevant articles and documents

Synthesis and radioiodination of some 9-aminoacridine derivatives for potential use in radionuclide therapy

Three derivatives of the DNA intercalating compound 9-aminoacridine, were prepared and radioiodinated for biological experiments. The compounds are the stannyl derivatives 3-{4-[3-(acridin-9-ylamino)-propoxy]-3-trimethylstannyl- phenyl}-propionic acid and acridin-9-yl-{3-[4-(2-amino-ethyl)-2- trimethylstannyl-phenoxy]-propyl}-amine which were synthesized from the corresponding iodo derivatives by palladium catalyzed reactions, and 4-[2-(acridin-9-ylamino)-ethyl]-phenol. The two stannylated compounds and the phenol were used as precursors for radioiodination and were labeled with 125I using chloramine-T as an oxidant achieving high-to-excellent yields. Copyright