92496-65-6

Basic information

• Product Name: 3'-HYDROXYFLAVANONE
• Synonyms: 3'-HYDROXYFLAVANONE;HYDROXYFLAVANONE, 3'
• CAS NO: 92496-65-6
• Molecular Formula: C₁₅H₁₂O₃
• Molecular Weight: 240.25
• Product Categories: Biochemistry;Flavonoids
• Mol File: 92496-65-6.mol
• Article Data: 13

Chemical Properties

• Melting Point: 138.0 to 142.0 °C
• Appearance: /
• CAS DataBase Reference: 3'-HYDROXYFLAVANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-HYDROXYFLAVANONE(92496-65-6)
• EPA Substance Registry System: 3'-HYDROXYFLAVANONE(92496-65-6)

Safety Data

• Hazardous Substances Data: 92496-65-6(Hazardous Substances Data)

Usage

Definition

ChEBI: A monohydroxyflavanone in which the hydroxy group is located at position 3'.

Upstream product

• 118-93-4 o-hydroxyacetophenone 
• 100-83-4 meta-hydroxybenzaldehyde 
• 491-38-3 1-benzopyran-4(4H)-one 
• 591-20-8 3-Bromophenol 
• 75848-97-4 2',3-dihydroxy-αβ-dihydrochalcone 
• 121245-86-1 1-(2-hydroxyphenyl)-3-(3-hydroxyphenyl)prop-2-en-1-one 
• 13709-05-2 3-methoxymethoxybenzaldehyde 
• 121245-86-1 (2E)-1-(2-hydroxyphenyl)-3-(3-hydroxyphenyl)-2-propen-1-one 
• 108-95-2 phenol 
• 491-37-2 2,3-dihydro-4H-1-benzopyran-4-one 
• 87199-18-6 3-hydroxyphenylboronic acid 
• 3055-86-5 3-phenoxypropionitrile 

Downstream Products

• 1386980-99-9 3-(4-oxochroman-2-yl)phenyl phenylcarbamate 
• 70460-18-3 3'-hydroxyflavone 
• 6563-37-7 3',4'-dihydroxyflavanone 

Relevant articles and documents

Divergent synthesis of flavones and flavanones from 2′-hydroxydihydrochalconesviapalladium(ii)-catalyzed oxidative cyclization

Divergent and versatile synthetic routes to flavones and flavanonesviaefficient Pd(ii) catalysis are disclosed. These Pd(ii) catalyses expediently provide a variety of flavones and flavanones from 2′-hydroxydihydrochalcones as common intermediates, depending on oxidants and additives,viadiscriminate oxidative cyclization sequences involving dehydrogenation, respectively, in a highly atom-economic manner.

A cationic cyclodextrin clicked bilayer chiral stationary phase for versatile chiral separation in HPLC

A cationic cyclodextrin (CD) clicked bilayer chiral stationary phase (CSP) was developed via click chemistry for chiral separations in multimode high-performance chromatography (HPLC). The versatility of this new CSP was evaluated using 17 model racemic pairs including aromatic alcohols, flavonoids and isoxazoline enantiomers in both reversed-phase (RP) and normal-phase (NP) HPLC. The CD functionality-enhanced chiral selectivity was elucidated in different elution modes. Higher chiral resolutions were shown in the RP-elution mode due to the inclusion complexation in comparison to the NP-elution mode. The highest chiral resolution of 4.40 was achieved for 4ClPh-OPr, with 12 racemic pairs baseline separated in RP-HPLC. The addition of organic modifiers in mobile phases plays an important role in optimizing the enantioselectivities of the cationic CD bilayer CSP in NP-HPLC.

Functionalities tuned enantioselectivity of phenylcarbamate cyclodextrin clicked chiral stationary phases in HPLC

The mixed chloro- and methyl- functionalities can greatly modulate the enantioselectivities of phenylcarbamate cyclodextrin (CD) clicked chiral stationary phases (CSPs). A comparison study is herein reported for per(4-chloro-3-methyl)phenylcarbamate and per(2-chloro-5-methyl)phenylcarbamate β-CD clicked CSPs (i.e., CCC4M3-CSP and CCC2M5-CSP). The enantioselectivity dependence on column temperature was studied in both normal-phase and reversed-phase mode high performance liquid chromatography (HPLC). The thermodynamic study revealed that the stronger intermolecular interactions can be formed between CCC4M3-CSP and chiral solutes to drive the chiral separation. The higher enantioselectivities of CCC4M3-CSP were further demonstrated with the enantioseparation of 17 model racemates in HPLC.