929256-65-5

Basic information

• Product Name: (E)-2-(4-Trifluoromethyl-phenyl)-ethenesulfonyl chloride
• Synonyms: (E)-2-(4-Trifluoromethyl-phenyl)-ethenesulfonyl chloride
• CAS NO: 929256-65-5
• Molecular Weight: 270.66
• Mol File: 929256-65-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-2-(4-Trifluoromethyl-phenyl)-ethenesulfonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-(4-Trifluoromethyl-phenyl)-ethenesulfonyl chloride(929256-65-5)
• EPA Substance Registry System: (E)-2-(4-Trifluoromethyl-phenyl)-ethenesulfonyl chloride(929256-65-5)

Safety Data

• Hazardous Substances Data: 929256-65-5(Hazardous Substances Data)

Upstream product

• 455-19-6 4-Trifluoromethylbenzaldehyde 
• 402-50-6 1-trifluoromethyl-4-vinyl-benzene 

Downstream Products

• 405262-78-4 (E)-N-[6-chloro-5-(2-methoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidin-4-yl]-2-(4-trifluoromethylphenyl)ethenesulfonamide 

Relevant articles and documents

Sulfonylated aminothiazoles as new small molecule inhibitors of protein phosphatases

Based on a previously identified lead structure, SC-ααδ9, we have developed a versatile new chemical scaffold that can be readily modified to generate libraries of both Tyr and dual specificity phosphatase inhibitors with reduced molecular weight and lipophilicity. The most potent analogue identified to date, aminothiazole 8z, inhibits the dual specificity phosphatase Cdc25B with a Ki of 4.6 ± 0.4 μM and a Hill coefficient of 2.