94350-85-3Relevant articles and documents
A straightforward synthesis of pyridopyrazino[2,3-b]indoles and indolo [2,3-b]-quinoxaline
Alphonse, France-Aimée,Routier, Sylvain,Coudert, Gérard,Mérour, Jean-Yves
, p. 925 - 940 (2007/10/03)
1,2-Diamines (ethylenediamine, o-phenylenediamine, 2,3-diamino-pyridine, 3,4-diaminopyridine) were reacted with 1-acetyl-2-bromo-3-indolinone to afford 5H-pyrazino[2,3-b]indoles, indolo[2,3-b]quinoxaline and pyridopyrazino[2,3-b]indole in good yields. Alkylation of the indolic nitrogen atom of these indolic derivatives with 2-chloroethylmorpholine, 2-chloroethyl-dimethylamine and allyl bromide was carried out in order to obtain the corresponding N-alkylated derivatives.