944-30-9Relevant articles and documents
Development of inhibitors of receptor protein tyrosine phosphatase β/ζ (PTPRZ1) as candidates for CNS disorders
Pastor, Miryam,Fernández-Calle, Rosalía,Di Geronimo, Bruno,Vicente-Rodríguez, Marta,Zapico, José María,Gramage, Esther,Coderch, Claire,Pérez-García, Carmen,Lasek, Amy W.,Puchades-Carrasco, Leonor,Pineda-Lucena, Antonio,de Pascual-Teresa, Beatriz,Herradón, Gonzalo,Ramos, Ana
, p. 318 - 329 (2018)
A new series of blood-brain barrier permeable molecules designed to mimic the activity of Pleiotrophin in the CNS has been designed and synthesized. These compounds exert their action by interacting with the intracellular domain PD1 of the Protein Tyrosin
Practical and efficient synthesis of aryl trifluoromethyl sulfones from arylsulfonyl chlorides with Umemoto's reagent II
Zhou, Xiaocong,Hu, Dufen,He, Xinyi,Li, Yuanqiang,Chu, Youqun,She, Yuanbin
supporting information, (2019/12/24)
A practical and efficient method for the synthesis of aryl trifluoromethyl sulfones has been developed by a tandem reaction of arylsulfonyl chlorides with Umemoto's reagent II. The advantageous features of this method are simple operation, mild reaction conditions, wide scope of substrates, high yield of products, and easy scalability.
Copper-catalyzed trifluoromethylation of arylsulfinate salts using an electrophilic trifluoromethylation reagent
Lin, Xiaoxi,Wang, Guimei,Li, Huaifeng,Huang, Yuanyuan,He, Weiming,Ye, Dandan,Huang, Kuo-Wei,Yuan, Yaofeng,Weng, Zhiqiang
, p. 2628 - 2632 (2013/03/29)
A copper-catalyzed method for the trifluoromethylation of arylsulfinates with Togni's reagent has been developed, affording aryltrifluoromethylsulfones in moderate to good yields. A wide range of functional groups in arylsulfinates are compatible with the
