94838-59-2

Basic information

• Product Name: [2-(4-AMINO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER
• Synonyms: [2-(4-AMINO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER;TERT-BUTYL-2-(4-AMINOPHENYL)ETHYLCARBAMATE;CarbaMic acid, N-[2-(4-aMinophenyl)ethyl]-, 1,1-diMethylethyl ester;4-[2-(Boc-aMino)ethyl]aniline;4-(2-Aminoethyl)aniline, 4-BOC protected;tert-Butyl [2-(4-aminophenyl)ethyl]carbamate, 4-{2-[(tert-Butoxycarbonyl)amino]ethyl}aniline;tert-Butyl N-[2-(4-aminophenyl)ethyl]carbamate
• CAS NO: 94838-59-2
• Molecular Formula: C₁₃H₂₀N₂O₂
• Molecular Weight: 236.31
• Product Categories: pharmacetical
• Mol File: 94838-59-2.mol
• Article Data: 46

Chemical Properties

• Boiling Point: 396.8±25.0 °C(Predicted)
• Appearance: Brown/Solid
• Density: 1.077±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• PKA: 12.81±0.46(Predicted)
• Water Solubility: Slightly soluble in water.
• CAS DataBase Reference: [2-(4-AMINO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: [2-(4-AMINO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER(94838-59-2)
• EPA Substance Registry System: [2-(4-AMINO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER(94838-59-2)

Safety Data

• RIDADR: 2811
• HazardClass: 6.1
• PackingGroup: Ⅲ
• Hazardous Substances Data: 94838-59-2(Hazardous Substances Data)

Usage

Uses

4-[2-(Boc-amino)ethyl]aniline is used as a intermediate for chemical research.

Upstream product

• 144226-16-4 (tert-butoxy)-N-[2-(4-nitrophenyl)-ethyl]-carboxamide 
• 13472-00-9 p-Aminophenethylamine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 24954-67-4 2-(p-nitrophenyl)ethylamine 
• 63630-08-0 N-[4-(2-aminoethyl)phenyl]acetamide 
• 3544-25-0 p-aminophenylacetonitrile 
• 541-16-2 t-butyl malonate 
• 7439-89-6 iron 
• 29968-78-3 2-(4-nitrophenyl)ethylamine monohydrochloride 
• 34619-03-9 tert-butyldicarbonate 

Downstream Products

• 182315-22-6 3-{2-[4-(2-tert-butoxycarbonylamino-ethyl)-phenylcarbamoyl]-vinyl}-4,6-dichloro-1H-indole-2-carboxylic acid ethyl ester 
• 390404-98-5 [2-(4-{3-[2-(3,4-dichloro-phenyl)-2-hydroxy-ethyl]-3-isopropyl-ureido}-phenyl)-ethyl]-carbamic acid tert-butyl ester 
• 392621-86-2 tert-Butyl 4-[(1-benzyl-4-piperidinyl)amino]phenethylcarbamate 
• 714568-74-8 tert-butyl 2-[4-(4H-1,2,4-triazol-4-yl)phenyl]ethyl-carbamate 
• 849540-68-7 (R)-[4-(2-tert-butoxycarbonylaminoethyl)phenylcarbamoyl]phenyl-methylcarbamic acid tert-butyl ester 
• 849540-58-5 (S)-[4-(2-tert-butoxycarbonylaminoethyl)phenylcarbamoyl]phenyl-methylcarbamic acid tert-butyl ester 
• 859517-88-7 [2-(4-acetylamino-3-chloro-phenyl)-ethyl]-carbamic acid tert-butyl ester 
• 853908-51-7 {2-[4-(6-bromo-3-nitro-quinolin-4-ylamino)-phenyl]-ethyl}-carbamic acid tert-butyl ester 
• 616893-71-1 tert-butyl 2-[4-(propanimidoylamino)phenyl]ethylcarbamate 
• 1057249-39-4 (2-{4-[3-(3-methoxy-phenyl)-ureido]-phenyl}-ethyl)-carbamic acid tert-butyl ester 
• 522602-06-8 [2-(4-benzoylamino-phenyl)-ethyl]-carbamic acid tert-butyl ester 
• 875798-26-8 {2-[4-(3-trifluoromethyl-benzoylamino)-phenyl]-ethyl}-carbamic acid tert-butyl ester 
• 177270-26-7 [2-(4-Amino-3-iodo-phenyl)-ethyl]-carbamic Acid Tert-Butyl Ester 
• 372095-35-7 N-[4-(2-tert-butoxycarbonylaminoethyl)phenyl]-(2-chloro-5-nitrophenyl)carboxamide 

Relevant articles and documents

Cannabinoid receptor light-operated ligand and preparation method and application thereof

The invention relates to the technical field of biology, in particular to a novel cannabinoid receptor light-operated ligand and a preparation method and application thereof. Disclosed is the cannabinoid receptor light-operated ligand or the isomer prodrug, the solvate and the pharmaceutically acceptable salt of the cannabinoid receptor light-operated ligand, wherein the structural formula of thecannabinoid receptor light-operated ligand is A-linker-B; A is a transmembrane domain ligand structure, and B is a light-operated element; Linker is a subunit which is linear and has no activity on acannabinoid receptor light-operated ligand. According to the invention, the cannabinoid receptor ligand is integrated with azobenzene through a proper connector, so that the ligand configuration is changed under an illumination condition, and the activation or inhibition state of the cannabinoid receptor is regulated and controlled.

Rational Remodeling of Atypical Scaffolds for the Design of Photoswitchable Cannabinoid Receptor Tools

Azobenzene-embedded photoswitchable ligands are the widely used chemical tools in photopharmacological studies. Current approaches to azobenzene introduction rely mainly on the isosteric replacement of typical azologable groups. However, atypical scaffolds may offer more opportunities for photoswitch remodeling, which are chemically in an overwhelming majority. Herein, we investigate the rational remodeling of atypical scaffolds for azobenzene introduction, as exemplified in the development of photoswitchable ligands for the cannabinoid receptor 2 (CB2). Based on the analysis of residue-type clusters surrounding the binding pocket, we conclude that among the three representative atypical arms of the CB2 antagonist, AM10257, the adamantyl arm is the most appropriate for azobenzene remodeling. The optimizing spacer length and attachment position revealed AzoLig 9 with excellent thermal bistability, decent photopharmacological switchability between its two configurations, and high subtype selectivity. This structure-guided approach gave new impetus in the extension of new chemical spaces for tool customization for increasingly diversified photo-pharmacological studies and beyond.

PESTICIDAL COMPOSITIONS AND METHODS

This disclosure relates to the field of molecules having pesticidal utility against pests in phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such molecules and intermediates used in such processes, compositions containing such molecules, and processes of using such molecules against such pests. These molecules may be used, for example, as nematicides, acaricides, insecticides, miticides, and/or molluscicides. This document discloses molecules having the structure of Formula A.