96795-00-5Relevant articles and documents
PROCESS FOR PREPARING OXAZOLINE-PROTECTED AMINODIOL COMPOUNDS USEFUL AS INTERMEDIATES TO FLORFENICOL
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Page/Page column 50-51, (2010/04/03)
Processes for preparing oxazoline compounds are disclosed. These oxazoline compounds are useful intermediates in the preparation of Florfenicol and related compounds.
An enzymatic route to florfenicol
Clark,Fischer,Schumacher
, p. 891 - 894 (2007/10/02)
Racemic ethyl threo-3-14-methylthiophenyl)serinate is resolved by enzymatic hydrolysis using protease from Streptomyces griseus and both stereoisomers are converted to D-threo-4,5-dihydro-5-(4-methylsulfonylphenyl)-2-phenyl-4-oxazolemethan ol, thereby giving a formal synthesis of florfenicol.