Welcome to LookChem.com Sign In | Join Free
Home > Products > mandelonitrile synthesis

mandelonitrile synthesis

  • Product Details
  • Company Profile

    Mandelonitrile synthesis


    As the method of producing a mandelonitrile compound, it comprises reacting a benzaldehyde compound and hydrogen cyanide in the presence of an alkali metal salt in a water solvent. when the benzaldehyde compound has a substituent at an ortho position, the substituent hinders the reaction, and the yield of a mandelonitrile compound is not satisfactory in some cases.

     

    The present invention has an object of providing a method for producing a mandelonitrile compound in good yield from a benzaldehyde compound having a prescribed substituent at an ortho position.


    The present inventors have intensively studied and resultantly found that the above-described object can be attained by reacting a benzaldehyde compound having a prescribed substituent at an ortho position with hydrogen cyanide in an amount of 1.2 to 5 mol with respect to 1 mol of the benzaldehyde compound, in the presence of an organic base in an organic solvent, leading to completion of the present invention. 

Verified Supplier

Escrow ServiceMore
Secure Your Orders With escrow More Transparency,Less Uncertainty

Send a message direct to supplier(s)

*From:
Enter email or Member ID
To:
JiangXi Keyuan Biopharma Co., LTD.
Subject:
*Message:

-Enter between 20 to 2000 letters.English only. Word count:0 letter(s).
-We suggest you include in your inquiry a brief introduction to your company as well as your product requirements
 

Related products