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Saxagliptin cost

How the saxagliptin is produced and what it cost?
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    1. The overview of saxagliptin
    Saxagliptin
    whose CAS Registry Number is 361442-04-8 is a drug which was developed for the treatment of respiratory disorders such as asthma and Chronic Obstructive Pulmonary Disease (COPD). It is orally active and acts as a selective Phosphodiesterase-4 inhibitor. Saxagliptin hydrochloride is the most common form. Saxagliptin is produced industrially the amide coupling of N-Boc-3-hydroxyadamantylglycine (2) and methanoprolineamide (3) with EDC. The prolineamide moiety is subsequently dehydrated with trifluoroacetic anhydride to give the cyanide as the trifluoracetate ester, which is hydrolyzed. Removal of the Boc protecting group, followed by neutralization gives the desired product (1):


    2. Saxagliptin cost
    Saxagliptin price
    always ranges from US $1-700 / Gram (FOB Price). If you are planning to buy saxagliptin, you may choose saxagliptin suppliers like Bristol-Myers Squibb or the china saxagliptin suppliers like HANGZHOU HOLYPHARM BIOTECH CO.,LTD. When choose a saxagliptin supplier, you need to balance the saxagliptin cost and the quality of it. Always High Quality Saxagliptin 361442-04-8 needs more than others. Hence,  please check carefully the supplier qualification before order it.

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