865869-28-9

Basic information

• Product Name: 4,4-DIMETHYLCYCLOHEXEN-1-YLBORONIC ACID
• Synonyms: 4,4-(DIMETHYLCYCLOHEXEN-1-YL)BENZENEBORONIC ACID;4,4-DIMETHYLCYCLOHEXEN-1-YLBORONIC ACID;4,4-DIMETHYL-1-CYCLOHEXEN-1-YLBORONIC ACID;4,4-Dimethylcyclohexen-1-ylboronic acid 97%;4,4-DiMethylcyclohexene-1-boronic acid, 96%;(4,4-DiMethylcyclohex-1-en-1-yl)boronic acid;(4,4-Dimethylcyclohex-1-en-1-yl)boronic acid 98%;1-Borono-4,4-dimethylcyclohex-1-ene
• CAS NO: 865869-28-9
• Molecular Formula: C₈H₁₅BO₂
• Molecular Weight: 154.01
• Product Categories: blocks;BoronicAcids
• Mol File: 865869-28-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 152-154
• Boiling Point: 264.1 °C at 760 mmHg
• Flash Point: 113.5 °C
• Appearance: /
• Density: 1g/cm³
• Vapor Pressure: 0.00138mmHg at 25°C
• Refractive Index: 1.477
• Storage Temp.: Store below -20C
• PKA: 9.43±0.40(Predicted)
• CAS DataBase Reference: 4,4-DIMETHYLCYCLOHEXEN-1-YLBORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4-DIMETHYLCYCLOHEXEN-1-YLBORONIC ACID(865869-28-9)
• EPA Substance Registry System: 4,4-DIMETHYLCYCLOHEXEN-1-YLBORONIC ACID(865869-28-9)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 865869-28-9(Hazardous Substances Data)

Usage

General Description

4,4-DIMETHYLCYCLOHEXEN-1-YLBORONIC ACID is an organic compound with the chemical formula C10H15BO2. It is a boronic acid derivative that contains a cyclohexene ring with two methyl groups attached. 4,4-DIMETHYLCYCLOHEXEN-1-YLBORONIC ACID is commonly used in organic synthesis as a reagent for creating carbon-carbon bonds through the Suzuki coupling reaction. It is also used as a building block for the synthesis of various pharmaceuticals and agrochemicals. 4,4-DIMETHYLCYCLOHEXEN-1-YLBORONIC ACID is a useful tool in the field of organic chemistry for creating complex molecules with specific structural and functional properties.

InChI:InChI=1/C8H15BO2/c1-8(2)5-3-7(4-6-8)9(10)11/h3,10-11H,4-6H2,1-2H3

Upstream product

• 4255-62-3 4,4-dimethylcyclohexane-1-one 
• 64692-81-5 N'-(4,4-dimethylcyclohexylidene)-4-methylbenzene-1-sulfonohydrazide 
• 859217-67-7 2-(4,4-dimethylcyclohex-1-ene-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Downstream Products

• 954425-01-5 4-[2-(tert-butyl-dimethyl-silanyloxy)-1,1-dimethyl-ethyl]-2-(4,4-dimethyl-cyclohex-1-enyl)-phenylamine 
• 915006-24-5 2-(4,4-dimethyl-cyclohex-1-enyl)-3-nitro-pyridine 
• 1445871-63-5 C₂₁H₂₃NO₂ 
• 1445871-94-2 C₂₁H₂₃NO₂ 
• 1622453-05-7 C₁₅H₁₅F₃N₂ 
• 1190962-54-9 4-(2-amino-4-(4,4-dimethylcyclohex-1-en-1-yl)pyrimidin-5-yl)pyridin-3-yl trifluoromethanesulfonate 
• 1190962-52-7 4-(4,4-dimethylcyclohex-1-en-1-yl)-5-(3-methoxy-pyridin-4-yl)-pyrimidin-2-amine 
• 1190962-51-6 5-(3-chloro-pyridin-4-yl)-4-(4,4-dimethylcyclohex-1-en-1-yl)-pyrimidin-2-amine 
• 1190962-53-8 4-(2-amino-4-(4,4-dimethylcyclohex-1-en-1-yl)pyrimidin-5-yl)pyridin-3-ol 
• 1190962-50-5 5-bromo-4-(4,4-dimethyl-cyclohex-1-enyl)pyrimidin-2-amine 
• 907205-86-1 4-cyano-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazole-2-carboxylic acid [4-bromo-2-(4,4-dimethyl-cyclohex-1-enyl)-phenyl]-amide 
• 915006-26-7 4-cyano-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazole-2-carboxylic acid [2-(4,4-dimethyl-cyclohex-1-enyl)-pyridin-3-yl]-amide 
• 915006-25-6 2-(4,4-dimethyl-cyclohex-1-enyl)-pyridin-3-ylamine 
• 1403382-29-5 ethyl 2-(tert-butoxy)-2-[2-(4,4-dimethylcyclohex-1-en-1-yl)-6-(trifluoromethyl)phenyl]acetate 

Relevant articles and documents

Copper-catalyzed tri- or tetrafunctionalization of alkenylboronic acids to prepare tetrahydrocarbazol-1-ones and indolo[2,3-a]carbazoles

We describe a cascade strategy for tri- or tetrafunctionalization of alkenylboronic acids to prepare diverse tetrahydrocarbazol-1-ones and indolo[2,3-a]carbazoles in good yields withN-hydroxybenzotriazin-4-one (HOOBT) and arylhydrazines as oxygen and nitrogen sources, respectively. Mechanistic studies reveal that the domino reaction undergoes the copper-catalyzed Chan-Lam reaction, [2,3]-rearrangement, nucleophilic substitution, oxidation and sequential [3,3]-rearrangement over five steps in a one-pot reaction. The reaction shows a broad substrate scope and tolerates a wide range of functional groups. More importantly, the reaction is easily performed at gram scales and the product is purified by simple extraction, washing, and recrystallization without flash column chromatography. The present protocol features easily available starting materials, high site-marked functionalization, five-step cascade in one pot, multiple C-C/C-O/C-N bond formation, and diversity of indole motifs.

4-CARBOX PYRAZOLE DERIVATES USEFUL AS ANTI-VIRAL AGENTS

Novel antiviral compounds of Formula (I) : wherein: A represents hydroxy; R1 represents aryl, heteroaryl bonded through a ring carbon atom, or heterocyclyl bonded through a ring carbon atom, C1-6alkyl or -C5-9cycloalkyl, each of which may be optionally su