2-Propyloxetane

Base Information

• Chemical Name: 2-Propyloxetane
• CAS No.: 4468-64-8
• Molecular Formula: C6H12O
• Molecular Weight: 100.161
• Mol file: 4468-64-8.mol

Synonyms:Hexane,3-epoxy;Oxetane,2-propyl;2-propyl-oxetane;Hexane,1,3-epoxy;2-n-Propyloxetan;1,3-hexylene oxide;

Chemical Property of 2-Propyloxetane

Chemical Property:

• Vapor Pressure: 22.5mmHg at 25°C
• Boiling Point: 115.6°Cat760mmHg
• Flash Point: 14.7°C
• PSA: 9.23000
• Density: 0.862g/cm³
• LogP: 1.57540

Purity/Quality:

90%,98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Propyloxetane

There total 1 articles about 2-Propyloxetane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

hexane (110-54-3) → oxirane (75-21-8,99932-75-9) + 2-ethyltetrahydrofuran (1003-30-1,123931-62-4) + 2-ethyl-4-methyloxetane (5410-21-9) + 2,5-dimethyltetrahydrofuran (1003-38-9) + 2-methyloxane (10141-72-7) + 2,3-diethyloxirane (4468-66-0,36611-93-5,36611-94-6,124718-82-7,135559-58-9,149951-15-5) + 1,2-Epoxyhexane (1436-34-6) + 2,3-epoxyhexane (1192-32-1) + 2-propyl-oxetane (4468-64-8) + methanol (67-56-1) + Ketene (463-51-4) + formaldehyd (50-00-0,30525-89-4,61233-19-0) + propene (187737-37-7,13987-01-4,15220-87-8,9003-07-0,676-63-1,25085-53-4) + methane (34557-54-5,27936-85-2) + ethane (74-84-0) + ethene (74-85-1) + 1,2-propanediene (463-49-0) + acetaldehyde (75-07-0,9002-91-9) + acetic acid (64-19-7,77671-22-8) + propionic acid (802294-64-0,79-09-4) + buta-1,3-diene (106-99-0,130983-70-9,29406-96-0,9003-17-2) + methyloxirane (75-56-9,16033-71-9) + prop-1-yne (74-99-7) + acetylene (74-86-2,25067-58-7)

Guidance literature:

With oxygen; at 376.84 ℃; for 0.000555556h; under 795.08 Torr; Temperature; Inert atmosphere;

DOI:10.1021/jp503772h

Reference yield:

2-propyl-oxetane (4468-64-8) + 1-Phenyl-1H-tetrazole-5-thiol (86-93-1) → C13H18N4OS

Guidance literature:

With lithium bromide; In N,N-dimethyl-formamide; tert-butyl alcohol; at 20 ℃; for 36h; Inert atmosphere;

DOI:10.1021/acs.orglett.5b03202

Reference yield:

2-propyl-oxetane (4468-64-8) → C30H34O9S

Guidance literature:

Multi-step reaction with 10 steps

1.1: lithium bromide / tert-butyl alcohol; N,N-dimethyl-formamide / 36 h / 20 °C / Inert atmosphere

2.1: dmap; 1H-imidazole / dichloromethane / 16 h / 20 °C / Inert atmosphere

3.1: dihydrogen peroxide; ammonium molybdate / ethanol; water / 49 h / 0 - 20 °C

4.1: potassium hexamethylsilazane / tetrahydrofuran / -78 °C / Inert atmosphere

4.2: -78 - 20 °C / Inert atmosphere

5.1: 1,8-diazabicyclo[5.4.0]undec-7-ene; water / acetonitrile / 1 h / 50 °C

6.1: iodine; morpholine / dichloromethane / 1 h / 20 °C / Inert atmosphere

7.1: dmap; pyridine / 20 °C / Inert atmosphere

8.1: triethylamine; palladium diacetate / 72 h / 120 °C / Inert atmosphere; Sealed tube

9.1: tetrabutyl ammonium fluoride; acetic acid / 20 h / 20 °C / Inert atmosphere

10.1: dmap; pyridine / 16 h / 20 °C / Inert atmosphere

With morpholine; pyridine; 1H-imidazole; dmap; ammonium molybdate; tetrabutyl ammonium fluoride; water; dihydrogen peroxide; iodine; palladium diacetate; potassium hexamethylsilazane; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; lithium bromide; In tetrahydrofuran; ethanol; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile; tert-butyl alcohol; 4.1: |Julia-Kocienski Olefination / 4.2: |Julia-Kocienski Olefination;

DOI:10.1021/acs.orglett.5b03202

upstream raw materials:

hexane

Refernces