phenyl 2-(2-pyridyl)ethyl sulfide

Base Information

• Chemical Name: phenyl 2-(2-pyridyl)ethyl sulfide
• CAS No.: 21070-71-3
• Molecular Formula: C₁₃H₁₃NS
• Molecular Weight: 215.319
• Mol file: 21070-71-3.mol

Synonyms:phenyl 2-(2-pyridyl)ethyl sulfide

Chemical Property of phenyl 2-(2-pyridyl)ethyl sulfide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phenyl 2-(2-pyridyl)ethyl sulfide

There total 5 articles about phenyl 2-(2-pyridyl)ethyl sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-vinylpyridine (100-69-6,25014-15-7,27476-03-5,329041-71-6) + thiophenol (108-98-5) → phenyl 2-(2-pyridyl)ethyl sulfide (21070-71-3)

Guidance literature:

at 60 ℃; for 2.5h;

DOI:10.1246/bcsj.73.243

Reference yield:

2-ethynylpyridine (1945-84-2) + diphenyldisulfane (882-33-7) → phenyl 2-(2-pyridyl)ethyl sulfide (21070-71-3) + 2-[(Z)-2-(phenylsulfanyl)ethenyl]pyridine (1398412-70-8) + (E)-2-(2-(phenylthio)vinyl)pyridine (1398413-99-4)

Guidance literature:

diphenyldisulfane; With acetic acid; zinc;

2-ethynylpyridine; at 20 ℃; for 4h;

DOI:10.1002/ejoc.201402668

Reference yield:

α-picoline (109-06-8) + formaldehyd (50-00-0,30525-89-4,61233-19-0) + thiophenol (108-98-5) → phenyl 2-(2-pyridyl)ethyl sulfide (21070-71-3)

Guidance literature:

With acetic acid; at 120 ℃;

upstream raw materials:

2-vinylpyridine

thiophenol

benzene

α-picoline

Downstream raw materials:

2-(2-benzenesulfonyl-ethyl)-piperidine

Refernces

• 1、 Abou-Shehada, Sarah,Teasdale, Matthew C.,Bull, Steven D.,Wade, Charles E.,Williams, Jonathan M. J.. "Lewis acid activation of pyridines for nucleophilic aromatic substitution and conjugate addition". . p. 1083 - 1087. Retrieved 2015/03/30.
• 2、 Watanabe, Mitsuru,Suga, Seiji,Yoshida, Jun-Ichi. "Intramolecular assistance of electron transfer from heteroatom compounds. Electrochemical oxidation of 2-(2-pyridyl)ethyl-substituted ethers, sulfides, and selenides". . p. 243 - 247. Retrieved 2007/10/03.